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P437: Higher adalimumab maintenance regimens are more effective than standard maintenance doses in Crohn’s disease patients who have failed infliximabECCO '18 Vienna
Year: 2018
Authors:

N. Narula1*, T. Greener2, K. Boland2, A.H. Steinhart2, M. Silverberg2

1McMaster University, Gastroenterology, Hamilton, ON, Canada, 2Mount Sinai Hospital, Toronto, Canada

P438: Reinduction with ustekinumab in Crohn’s disease patients with a loss of response to treatmentECCO '18 Vienna
Year: 2018
Authors:

V. Heron1*, S. Restellini1,2, T. Bessissow1, C. Lemieux1, P. Lakatos1, G. Wild1, E. Seidman1, A. Bitton1, W. Afif1

1McGill University Health Centre, Department of Gastroenterology, Montreal, Canada, 2Geneva's University Hospitals and University of Geneva, Division of Gastroenterology and Hepatology, Geneva, Switzerland

P439: Monitoring inflammatory Bowel disease activity in a virtual biologic clinic: The effects of proactive therapeutic drug monitoring on patient reported outcome measuresECCO '18 Vienna
Year: 2018
Authors:

N. Mc Gettigan*, M. McNally, C. Deane, A. Keogh, R. Costello, E. Slattery

Galway University Hospital, Gastroenterology, Galway, Ireland

P440: Early changes in the pharmacokinetic profile of vedolizumab-treated patients with inflammatory bowel disease may predict response after dose optimisationECCO '18 Vienna
Year: 2018
Authors:

C. Gouynou1, L. Pouillon1,2*, H. Rousseau3, C. Zallot1, C. Baumann3, L. Peyrin-Biroulet1

1Nancy University Hospital, Department of Gastroenterology, Vandoeuvre-lès-Nancy, France, 2Imelda GI Clinical Research Centre, Department of Gastroenterology, Bonheiden, Belgium, 3Nancy University Hospital, Clinical Research Support Facility PARC, Vandoeuvre-lès-Nancy, France

P441: Higher education, professional occupation and upper socio-economic status is associated with lower adherence to medications in patients with inflammatory bowel diseaseECCO '18 Vienna
Year: 2018
Authors:

S.K. Tomar1*, S. Kedia2, N. Singh1, A.D. Upadhyay3, S. Bopanna1, D. Yadav1, S. Goyal1, S. Jain1, G. Makharia1, V. Ahuja1

1All India Institute of Medical Sciences, Department of Gastroenterology and Human Nutrition, New Delhi, India, 2All India Institute of Medical Sciences, Gastroenterology, New Delhi, India, 3All India Institute of Medical Sciences, Department of Biostatistics, New Delhi, India

P442: The additional value of cytapheresis therapy in patients with severe ulcerative colitis treated with oral tacrolimusECCO '18 Vienna
Year: 2018
Authors:

S. Takahashi*, M. Colvin, J. Toyosawa, M. Ishida, T. Kagawa, S. Kuraoka, Y. Aoyama, K. Okamoto, I. Sakakihara, K. Izumikawa, K. Yamamoto, S. Tanaka, M. Matsuura, S. Ishikawa, M. Wato, T. Hasui, T. Inaba

Kagawa Prefectural Central Hospital, Department of Gastroenterology, Takamatsu, Kagawa, Japan

P443: Systematic analysis of annual health resource utilisation and costs in hospitalised inflammatory bowel disease patients in SwitzerlandECCO '18 Vienna
Year: 2018
Authors:

A. Schoepfer1*, S. Vavricka2, B. Bruengger3, O. Reich3, E. Blozik3, C. Bähler3

1Centre Hospitalier Universitaire Vaudois, Gastroenterology and Hepatology, Lausanne, Switzerland, 2University Hospital Zurich, Zurich, Switzerland, 3Helsana Health Insurance, Zurich, Switzerland

P445: Patients with active perianal fistulas have a reduced physical health compared with Crohn’s patients without perianal fistulasECCO '18 Vienna
Year: 2018
Authors:

M. van der Voorn1,2*, M. Barnhoorn1, S. van Erp1, P. Maljaars3, M. Rodriquez Girondo4, A. Kaptein3, A. van der Meulen - de Jong1

1Leiden University Medical Center, Gastroenterology and Hepatology, Leiden, The Netherlands, 2HagaZiekenhuis, Gastroenterology and Hepatology, The Hague, The Netherlands, 3Leiden University Medical Center, Medical Psychology, Leiden, The Netherlands, 4Leiden University Medical Center, Medical Statistics, Leiden, The Netherlands

P446: Patient and public involvement in a clinical trial for perianal Crohn’s fistulaECCO '18 Vienna
Year: 2018
Authors:

K. Sahnan1*, A. Verjee2, S. Blackwell3, R. Sawyer2, S. Mannick4, M.J. Lee5, S.O. Adegbola1, P.J. Tozer1, N. Heywood6, A.L. Hart7, N.S. Fearnhead8

1St Mark's Hospital, Colorectal Surgery, London, UK, 2Patient representative, London, UK, 3Patient Representative, Liverpool, UK, 4Patient Representative, London, UK, 5Sheffield Teaching Hospitals NHS Trust, Northern General Hospital, Department of Colorectal Surgery, Sheffield, UK, 6University Hospital South Manchester, Department of Colorectal Surgery, Manchester, UK, 7St Mark’s Hospital, IBD/Physiology, London, UK, 8Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Department of Colorectal Surgery, Cambridge, UK

P447: Infliximab trough levels are decreasing overtime in patients with inflammatory bowel disease on maintenance treatment with infliximabECCO '18 Vienna
Year: 2018
Authors:

E. Orfanoudaki1*, M. Gazouli2, K. Foteinogiannopoulou1, E. Theodouraki1, E. Legaki2, I. Koutroubakis1

1University Hospital Heraklion, Department of Gastroenterology, Heraklion, Greece, 2University of Athens, School of Medicine, Department of Basic Medical Science, Laboratory of Biology, Athens, Greece

P448: Remission induction therapy with tacrolimus and biological combination therapy for severe ulcerative colitisECCO '18 Vienna
Year: 2018
Authors:

A. Ito*

Tokyo Women’s Medical University, Department of Gastroenterology, Tokyo, Japan

P449: Double assessment of ileal pouch-anal anastomosis before ileostomy reversalECCO '18 Vienna
Year: 2018
Authors:

A. Gklavas1*, G. Exarchos1, L. Metaxa2, G. Karamanolis1, I. Papaconstantinou1

1Aretaieion Hospital, 2nd Surgical Department, Athens, Greece, 2St Bartholomew’s Hospital, Radiology Department, London, UK

P450: Mind the gap: Why do physicians underestimate their patient's adherence?ECCO '18 Vienna
Year: 2018
Authors:

E. Broide1,2*, A. Ein Dor1,3, A. B Shitrit4, N. Ruhimovich5, H. Shirin1,2, F.M. Konikoff3,5, T. Naftali3,5

1Assaf Harofeh Medical Center, The Kamila Gonczarowski Institute of Gastroenterology Assaf Harofeh Medical Center, Zerifin, Israel, 2Tel Aviv University Sackler School of Medicine, Internal Medicine, Tel Aviv, Israel, 3Tel Aviv University Sackler School of Medicine, Internal Medicine, Tel Aviv, Israel, 4Shaare Zedek Medical Center, Department of Gastroenterology and Digestive Diseases, Jerusalem, Israel, 5Meir Medical Center, Gastroenterology, Kfar Saba, Israel

P451: Long-term surgical outcome of ileal pouch-anal anastomosis when used for well-defined Crohn’s diseaseECCO '18 Vienna
Year: 2018
Authors:

D. Mandel, K. Zaghiyan, P. Fleshner*

Cedars-Sinai Medical Center, Los Angeles, USA

P452: Medium to long-term outcomes in patients receiving accelerated dose infliximab induction for acute severe ulcerative colitis (ASUC) in a multi-centre cohortECCO '18 Vienna
Year: 2018
Authors:

D. Gibson1, M. McNally2*, J. Doherty1, A. Keogh2, D. Keegan1, K. Byrne1, U. Kennedy3, H. Mulcahy1, S. McKiernan3, F. MacCarthy3, L. Egan2,4, G. Cullen1,4, J. Sheridan1, S. Sengupta4,5, E. Slattery2,4, D. Kevans3,4, G. Doherty1,4

1St Vincent's University Hospital/UCD, Centre for Colorectal Disease, Dublin, Ireland, 2University Hospital Galway/NUIG, Galway, Ireland, 3St James' Hospital/TCD, Dublin, Ireland, 4Initiative IBD Research Network, Ireland, Ireland, 5Our Lady's Hospital Drogheda/RCSI, Drogheda, Ireland

P453: Pre-operative vedolizumab treatment and postoperative complications in patients with inflammatory bowel disease: A systematic review and meta-analysisECCO '18 Vienna
Year: 2018
Authors:

C. Law1, A. Narula2, A. Lightner3, J.-F. Colombel4, N.P. McKenna5, N. Narula2*

1McMaster University, Internal Medicine, Hamilton, Canada, 2McMaster University, Gastroenterology, Hamilton, Canada, 3Mayo Clinic, Colon and Rectal Surgery, Rochester, USA, 4Icahn School of Medicine at Mount Sinai, Gastroenterology, New York, USA, 5Mayo Clinic, Surgery, Rochester, USA

P454: Early vedolizumab trough levels predict mucosal healing in inflammatory bowel diseaseECCO '18 Vienna
Year: 2018
Authors:

W. Yacoub1, N. Williet2, L. Pouillon1,3*, T. Di-Bernado2, M. De Carvalho Bittencourt4, S. Nancey5, A. Lopez1, S. Paul6, C. Zallot1, X. Roblin2, L. Peyrin-Biroulet1

1Nancy University Hospital, Department of Gastroenterology, Vandoeuvre-lès-Nancy, France, 2Saint-Etienne University Hospital, Department of Gastroenterology, Saint-Etienne, France, 3Imelda GI Clinical Research Centre, Department of Gastroenterology, Bonheiden, Belgium, 4Nancy University Hospital, Department of Immunology, Nancy, France, 5Lyon-Sud Hospital, Department of Gastroenterology, Pierre-Bénite, France, 6Saint-Etienne University Hospital, Department of Immunology, Saint-Etienne, France

P455: Spacing of infliximab infusions over 8 weeks in patients with inflammatory bowel diseases in clinical remission: Final results of a retrospective multicentre French national cohortECCO '18 Vienna
Year: 2018
Authors:

G. Dufour1*, B. Pariente2, A. Amiot3, S. Viennot4, F. Zerbib5, L. Caillo6, S. Nancey7, P. Pouderoux6, F. Poullenot5, R. Altwegg1, L. Peyrin-Biroulet8, M. Nachury2, P. Blanc1, G. Pineton de Chambrun1

1Montpellier University Hospital, Gastroenterology, Montpellier, France, 2Lille University Hospital, Gastroenterology, Lille, France, 3Henri-Mondor University Hospital, Gastroenterology, Creteil, France, 4Caen University Hospital, Gastroenterology, Caen, France, 5Bordeaux University Hospital, Gastroenterology, Bordeaux, France, 6CHU University Hospital, Department of Hepatology and Gastroenterology, Nîmes, France, 7Lyon University Hospital, Gastroenterology, Lyon, France, 8Nancy University Hospital, Gastroenterology, Nancy, France

P456: Drug survival of thiopurine–allopurinol combination therapy in a real-life population-based cohortECCO '18 Vienna
Year: 2018
Authors:

J.E. Kreijne1*, R.C. de Veer1, N.K. de Boer2, G. Bouma2, G. Dijkstra3, R.L. West4, A.A. van Bodegraven5, D.J. de Jong6, C.J. van der Woude1, A.C. de Vries1

1Erasmus MC, Gastroenterology and Hepatology, Rotterdam, The Netherlands, 2VU University Medical Centre, Gastroenterology and Hepatology, Amsterdam, The Netherlands, 3University Medical Center Groningen and University of Groningen, Gastroenterology and Hepatology, Groningen, The Netherlands, 4Franciscus Hospital and Vlietland Hospital, Gastroenterology and Hepatology, Rotterdam, The Netherlands, 5Zuyderland Medical Center, Clinical Gastroenterology and Hepatology, Heerlen-Sittard-Geleen, The Netherlands, 6Radboud University Nijmegen Medical Center, Gastroenterology and Hepatology, Nijmegen, The Netherlands

P457: Biological interventions for induction and maintenance of mucosal healing in ulcerative colitis: A Cochrane systematic reviewECCO '18 Vienna
Year: 2018
Authors:

A. Ricciuto1*, A. Al-Darmaki2, M.J. Stewart2, N.S. Ding3, H.H. Shim2, M. Storr4,5, R. Panaccione2, C. Seow2

1Hospital for Sick Children, University of Toronto, Toronto, Canada, 2University of Calgary, Medicine, Calgary, Canada, 3Imperial College Healthcare, London, UK, 4Ludwig-Maximilians-University Munich, Munich, Germany, 5Center of Endoscopy, Starnberg, Germany