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OP28 Gene expression (GE) values in a phase 2 trial of mirikizumab in ulcerative colitis (UC) correlate better with histopathology (HP) than endoscopy (EN) and Mayo scores
Year: 2020
Source:

ECCO'20 Vienna

Authors:

B. Steere1, K. GOTTLIEB1, J. Schmitz2, R. Higgs1, B. Jia1, C. Milch1, J. Tuttle3, V. Krishnan1, R. Belin1, W. Reinisch4

Created: Thursday, 30 January 2020, 10:12 AM
OP28: A randomized placebo controlled clinical trial with 5-hydroxytryptophan in patients with quiescent Inflammatory Bowel Disease and fatigue (Trp-IBD)
Year: 2022
Source: ECCO'22
Authors: Truyens, M.(1,2,3);Lobaton, T.(1,3);Peeters, A.(1);Ferrante, M.(4,5);Vermeire, S.(4,5);Bossuyt, P.(6);Pouillon, L.(6);Dewint, P.(7,8);Cremer, A.(9);Peeters, H.(10);Lambrecht, G.(11);Louis, E.(12);Rahier, J.F.(13);Dewit, O.(14);Muls, V.(15);Holvoet, T.(1,16);Vandermeulen, L.(17);Gonzales, G.B.(2,3,18);Laukens, D.(2,3);De Vos, M.(3);
Created: Friday, 11 February 2022, 3:52 PM
OP28: Children and young adults with inflammatory bowel disease have an increased incidence and risk of developing mental health conditions: a UK population-based cohort study
Year: 2023
Source: ECCO’23 Copenhagen
Authors: Cooney, R.(1)*;Tang, D.(2);Barrett, K.(3);Russell, R.K.(4);
Created: Friday, 14 July 2023, 10:43 AM
OP28: Host–microbial crosstalk in the pathogenesis of inflammation and cancer in primary sclerosing cholangitis
Year: 2019
Source:

ECCO '19 Copenhagen

Authors:

M. Neyazi1, N. Ilott2, Oxford IBD Cohort Study Investigators1, S. Travis1, C. Arancibia1, F. Powrie2, A. Geremia*1

Created: Friday, 22 February 2019, 9:41 AM
OP28: The effect of guselkumab induction therapy on early clinical outcome measures in patients with Moderately to Severely Active Crohn’s Disease: Results from the phase 2 GALAXI 1 study
Year: 2021
Source: ECCO'21 Virtual
Authors: Danese, S.(1);Sandborn, W.J.(2);Feagan, B.G.(3);Weisel, K.(4);Gonzalez, S.(4);Frustaci, M.E.(4);Yang, Z.(4);Johanns, J.(4);Germinaro, M.(4);Afzali, A.(5);Andrews, J.M.(6);D’Haens, G.(7);Hisamatsu, T.(8);Panaccione, R.(9);Reinisch, W.(10);Rubin, D.T.(11);Sands, B.E.(12);Panes, J.(13)
Created: Wednesday, 2 June 2021, 4:12 PM
OP29 Tofacitinib in ulcerative colitis: Real-world evidence from Eneida Registry
Year: 2020
Source:

ECCO'20 Vienna

Authors:

M. Chaparro1, A. Garre1, F. Mesonero2, C. Rodríguez3, M. Barreiro-de Acosta4, J. Martínez-Cadilla5, M.T. Arroyo6, N. Manceñido7, M. Sierra-Ausín8, I. Vera-Mendoza9, M.J. Casanova1, P. Nos10, C. González-Muñoza11, T. Martínez12, M. Boscá-Watts13, D. Busquets14, M. Calafat15, E. Girona16, J. Llaó17, M.D. Martín-Arranz18, M. Piqueras19, L. Ramos20, G. Suis21, F. Bermejo22, A.Y. Carbajo23, D. Casas-Deza24, A. Fernández-Clotet25, M.J. García26, D. Ginard27, A. Gutiérrez-Casbas28, L. Hernández-Villalba29, A.J. Lucendo30, L. Márquez31, O. Merino-Ochoa32, F.J. Rancel33, C. Taxonera34, A. López Sanromán2, S. Rubio3, E. Domènech15, J.P. Gisbert1

Created: Thursday, 30 January 2020, 10:12 AM
OP29: Long-term dietary patterns are associated with pro-inflammatory and anti-inflammatory features of the gut microbiome
Year: 2021
Source: ECCO'21 Virtual
Authors: Bolte, L.(1,2);Vich Vila, A.(1,2);Imhann, F.(1,2);Collij, V.(1,2);Peters, V.(1);Fu, J.(2,3);Kurilshikov, A.(2);Campmans-Kuijpers, M.(1);Dijkstra, G.(1);Wijmenga, C.(2);Zhernakova, A.(2);Weersma, R.(1)
Created: Wednesday, 2 June 2021, 4:12 PM
OP29: Peri-natal exposure to parental Crohn's disease is associated with impaired gut barrier, microbiome composition differences and increased risk of Crohn's disease
Year: 2023
Source: ECCO’23 Copenhagen
Authors: LeeDr., S.H.(1)*;Qiu, L.(1);A. Olivera, P.(1);Leibovitzh, H.(1);Xue, M.(1);Neustaeter, A.(1);Mbareche, H.(1);Xu, W.(2);Espin-Garcia, O.(2); L. Aumais, G.(3);Q. Huynh, H.(4);Panaccione, R.(5);Steinhart, A.H.(1);Cino, M.(6);Mack, D.(7);K. Marshall, J.(8);Ropeleski, M.(9);Bitton, A.(10);Jacobson, K.(11);McGraft, J.(12);Yerushalmi, B.(13);Abreu, M.(14);N. Bernstein, C.(15);Radford-Smith, G.(16);Lees, C.(17);Turner, D.(18);L. Madsen, K.(4);S. Guttman, D.(19);S. Silverberg, M.(1);Turpin, W.(1);Croitoru, K.(1);
Created: Friday, 14 July 2023, 10:43 AM
OP29: Peripheral blood DNA methylation biomarkers accurately predict clinical- and endoscopic response to vedolizumab in a real-life cohort of Crohn’s Disease patients
Year: 2022
Source: ECCO'22
Authors: Joustra, V.(1);Hageman, I.(1,2);Li Yim, A.(2,3);Levin, E.(4,5);Satsangi, J.(6);Adams, A.(6);De Jonge, W.(2);Henneman, P.(3);D'Haens, G.(1); on behalf of the EPIC consortium
Created: Friday, 11 February 2022, 3:52 PM
OP29: ST2+/IL-33 responsive cells promote tumorigenesis in colitis-associated colorectal cancer
Year: 2019
Source:

ECCO '19 Copenhagen

Authors:

L. R. Lopetuso*1, C. De Salvo2, L. Di Martino2, W. Goodman2, F. Scaldaferri1, A. Armuzzi1, A. Gasbarrini1, T. T. Pizarro2

Created: Friday, 22 February 2019, 9:41 AM
OP30 The interplay of microbiome dysbiosis and immune system deregulation in patients with Crohn’s disease
Year: 2020
Source:

ECCO'20 Vienna

Authors:

N.S. Seyed Tabib1, C. Caenepeel1, K. Machiels1, S. Verstockt1, B. Verstockt1,2, N. Ardeshir Davani1, J. Sabino1,2, M. Ferrante1,2, S. Vermeire1,2

Created: Thursday, 30 January 2020, 10:12 AM
OP30: Human umbilical cord mesenchymal stem cells derived exosomes alleviate Ulcerative Colitis by inhibiting macrophage ferroptosis via miR-23b-3p/Nrf2 pathway
Year: 2023
Source: ECCO’23 Copenhagen
Authors: Liu, L.(1)*;Zhao, J.(1);Ye, Y.(1);Feng, Z.(1);Wang, X.(1);Cao, X.(1);
Created: Friday, 14 July 2023, 10:43 AM
OP30: Lyophilised orally administered faecal microbiota transplantation for Active Ulcerative Colitis (LOTUS study)
Year: 2021
Source: ECCO'21 Virtual
Authors: Haifer, C.(1);Saikal, A.(2);Paramsothy, S.(1);Borody, T.J.(3);Ghaly, S.(2);Kaakoush, N.O.(4);Leong, R.(1)
Created: Wednesday, 2 June 2021, 4:12 PM
OP30: Serum proteomic profiling predicts and diagnoses pouchitis in ulcerative colitis patients undergoing ileal pouch-anal anastomosis
Year: 2019
Source:

ECCO '19 Copenhagen

Authors:

K. Machiels*1, M. Ferrante1,2, N. Davani1, A. Wolthuis3, A. D’Hoore3, S. Vermeire1,2

Created: Friday, 22 February 2019, 9:41 AM
OP30: Upadacitinib modulates inflammatory pathways in gut tissue in patients with Ulcerative Colitis: Transcriptomic profiling from the Phase 2b study, U-ACHIEVE
Year: 2022
Source: ECCO'22
Authors: Verstockt, B.(1);Blink Polakow, S.(2);Mahi, N.(2);Lee, J.(2);Wang, J.(3);Guay, H.(4);Salas, A.(5);Panés, J.(5);Ungaro, R.C.(6);Vermeire, S.(1);
Created: Friday, 11 February 2022, 3:52 PM
OP31 Meta–omics reveals microbiome-driven proteolysis as a contributing factor to the severity of ulcerative colitis disease activity
Year: 2020
Source:

ECCO'20 Vienna

Authors:

R. Mills1, P. Dulai2, Y. Vázquez-Baeza3, Q. Zhu3, G. Humphrey3, L. DeRight Goldasich3, R. Quinn4, A. Gewirtz5, B. Chassaing5, H. Chu6, W. Sandborn2, P. Dorrestein1, R. Knight3, D. Gonzalez1

Created: Thursday, 30 January 2020, 10:12 AM
OP31: Dietary and Multi-Omic characterization of new onset treatment naive Crohn Disease identifies factors that may contribute to disease pathogenesis
Year: 2022
Source: ECCO'22
Authors: Haberman Ziv, Y.(1);Braun, T.(1);Amir, A.(1);Levhar , N.(1);Malik, A.(1);Neuman, S.(1);Picard, O.(1);Yavzuri, M.(1);Efroni, G.(1);Hadar, R.(1);Ben-Horin, S.(1);
Created: Friday, 11 February 2022, 3:52 PM
OP31: High fat diet exacerbates colitis through microbial metabolite deoxycholic acids induced-ferroptosis
Year: 2023
Source: ECCO’23 Copenhagen
Authors: Wang, C.(1)*;Gu, Y.(1);Cao, H.(1);
Created: Friday, 14 July 2023, 10:43 AM
OP31: RESTORE: Interim analysis of a Phase 2 study of QBECO SSI for the induction and maintenance of clinical and endoscopic remission in subjects with Moderate to Severe Crohn’s Disease
Year: 2021
Source: ECCO'21 Virtual
Authors: Bressler, B.(1);Marshall, J.K.(2);Atkinson, K.(3);Sutcliffe, S.(4);Pankovich, J.(4);Jones, M.(4);Kalyan, S.(4);Gunn, H.(4)
Created: Wednesday, 2 June 2021, 4:12 PM
OP31: TP53 mutation in human colonic organoids acquires resistance to in vitro long-term inflammation
Year: 2019
Source:

ECCO '19 Copenhagen

Authors:

K. Tsuchiya*1, S. Watanabe1, T. Shirasaki1, R. Nishimura1, N. Katsukura1, S. Hibiya1, R. Okamoto1, T. Nakamura1, M. Watanabe1

Created: Friday, 22 February 2019, 9:41 AM