OP20: The effects of upadacitinib on ulcerative colitis symptom resolution and fatigue normalization in patients with moderately to severely active ulcerative colitis: Phase 3 U-ACHIEVE and U-ACCOMPLISH resultsECCO’23 CopenhagenYear: 2023
Authors: D'Haens, G.(1)*;Tran, J.(2,3);Danese, S.(4);Rubin, D.T.(5);Aoyama, N.(6);Lügering, A.(7);Klaff, J.(3);Xuan, S.(3);Ilo, D.(3);Sanchez Gonzalez, Y.(3);Panes, J.(8);
(1)Amsterdam University Medical Centres, Department of Gastroenterology and Hepatology, Amsterdam, The Netherlands;(2)University of Washington, The Comparative Health Outcomes- Policy- and Economics Institute, Seattle, United States;(3)AbbVie Inc., n/a, Chicago, United States;(4)University Vita-Salute San Raffaele, n/a, Milan, Italy;(5)University of Chicago Medicine, Inflammatory Bowel Disease Center, Chicago, United States;(6)Aoyama Medical Clinic, Department of Gastroenterology- Gastrointestinal Endoscopy and IBD Center, Kobe, Japan;(7)MVZ Portal10, n/a, Münster, Germany;(8)Hospital Clinic Barcelona- IDIPABS- CIBERehd, n/a, Barcelona, Spain;
OP21: COVID-19 morbidity/mortality and vaccination against SARS-CoV-2 in patients with Inflammatory Bowel Disease in Poland: Nationwide DataECCO’23 CopenhagenYear: 2023
Authors: Kucha, P.(1,2)*;Walkiewicz, D.(3);Wieszczy, P.(2,4);Reguła, J.(1,2);Zagórowicz, E.(1,2);
(1)Maria Skłodowska-Curie National Research Institute of Oncology, Department of Oncological Gastroenterology, Warsaw, Poland;(2)Centre of Postgraduate Medical Education, Department of Gastroenterology- Hepatology and Clinical Oncology, Warsaw, Poland;(3)Ministry of Health, Department of Analyses and Strategies, Warsaw, Poland;(4)Institute of Health and Society, Clinical Effectiveness Research Group, Oslo, Norway;
OP22: The risk of cancer in pediatric-onset immune-mediated inflammatory diseases – a nationwide Danish study from 1980-2018.ECCO’23 CopenhagenYear: 2023
Authors: Ehrström, A.(1)*;Jansson, S.(1);Malham, M.(1);Wewer, V.(1);
(1)Copenhagen IBD Center- Amager Hvidovre Hospital- University of Copenhagen, Department of Pediatrics and Adolescent Medicine, Hvidovre, Denmark;
OP23: Asymptomatic inflammatory bowel disease diagnosed during the colorectal cancer population screening in CataloniaECCO’23 CopenhagenYear: 2023
Authors: Brunet, E.(1,2)*;Selva, A.(3,4);Bas-Cutrina, F.(5);Brujats, A.(6,7);Caballol, B.(8);Gomez, B.(9);Gonzalez, C.(7);Busquets, D.(10);Monfort, D.(11);Vera, D.P.(12);Maristany, E.(13);Cirera, G.(14);Torres, G.(15);Castro-Poceiro, J.(16);Lopez, J.(17);Gonzalez-Gonzalez, L.(18);Marquez-Mosquera, L.(19);Gallach, M.(20);Esteve, M.(21);Tremosa, G.(22);Torra, S.(23);Robles, V.(24);Rodríguez-Lago, I.(25);Calvet, X.(2,26,27);
(1)Hospital Parc Taulí, Gastroenterology department, Sabadell, Spain;(2)Instituto de Salud Carlos III, CIBERehd, Madrid, Spain;(3)Hospital Universitari Parc Taulí, Clinical epidemiology and cancer screening, Sabadell, Spain;(4)Universitat Autònoma de Barcelona, Department of Pediatrics- Obstetrics- Gynecology and Preventive Medicine, Bellaterra, Spain;(5)Hospital General de Granollers, Gastroenterology department, Granollers, Spain;(6)Hospital de Berga - Salut Catalunya Central, Gastroenterology department, Berga, Spain;(7)Hospital de la Santa Creu i Sant Pau de Barcelona, Gastroenterology department, Barcelona, Spain;(8)Hospital Clínic de Barcelona, Gastroenterology department, Barcelona, Spain;(9)Hospital de Mataró, Gastroenterology department, Mataró, Spain;(10)Hospital Universitari de Girona Dr. J. Trueta, Gastroenterology department, Girona, Spain;(11)Consorci Sanitari de Terrassa, Gastroenterology department, Terrassa, Spain;(12)Hospital de Martorell, Gastroenterology department, Martorell, Spain;(13)Hospital de Bellvitge, Gastroenterology department, Bellvitge, Spain;(14)Hospital Althaia, Gastroenterology department, Manresa, Spain;(15)Hospital Universitari Arnau de Vilanova, Gastroenterology department, Lleida, Spain;(16)Sant Joan Despí Moisès Broggi, Gastroenterology department, Barcelona, Spain;(17)Hospital Universitari Joan XXIII, Gastroenterology department, Tarragona, Spain;(18)Hospital Germans Tries I Pujol, Gastroenterology department, Badalona, Spain;(19)Hospital del Mar, Gastroenterology department, Barcelona, Spain;(20)Hospital Universitari de Vic, Gastroenterology department, Vic, Spain;(21)Hospital Mutua de Terrassa, Gastroenterology department, Terrassa, Spain;(22)Hospital Comarcal de l'Alt Penedès, Gastroenterology department, Barcelona, Spain;(23)Parc Sanitari Sant Joan de Déu, Gastroenterology department, Barcelona, Spain;(24)Hospital Vall d'Hebron, Gastroenterology department, Barcelona, Spain;(25)Hospital de Galdakao- Galdakao, Gastroenterology department, Vizcaya, Spain;(26)Hospital Universitari Parc Taulí, Gastroenterology department, Sabadell, Spain;(27)Universitat Autònoma de Barcelona, Medicine departament, Bellaterra, Spain;
OP24: Neutralising antibody potency against SARS-CoV-2 wild-type and Omicron BA.1 and BA.4/5 variants in infliximab and vedolizumab treated patients with Inflammatory Bowel Disease after three doses of COVID-19 vaccine: a prospective multicentre cohort studyECCO’23 CopenhagenYear: 2023
Authors: Liu, Z.(1)*;Le, K.(1);Zhou, X.(1);Alexander, J.(1);Lin, S.(2);Bewshea, C.(2);Chanchlani, N.(2);Nice, R.(3);McDonald, T.(3);Lamb, C.(4);Sebastian, S.(5);Kok, K.(6);Lees, C.(7);Hart, A.(1);Pollok, R.(8);Boyton, R.(9);Altmann, D.(10);Pollock, K.(9);Goodhand, J.(2);Kennedy, N.(2);Ahmad, T.(2);Powell, N.(1);
(1)Imperial College London, Department of Metabolism Digestion and Reproduction, London, United Kingdom;(2)Royal Devon University Healthcare NHS Foundation Trust, Department of Gastroenterology, Exeter, United Kingdom;(3)Royal Devon University Healthcare NHS Foundation Trust, Department of Biochemistry, Exeter, United Kingdom;(4)Newcastle upon Tyne Hospitals NHS Foundation Trust, Department of Gastroenterology, Newcastle, United Kingdom;(5)Hull University Teaching Hospitals NHS Trust, Department of Gastroenterology, Hull, United Kingdom;(6)Barts Health NHS Trust, Department of Gastroenterology, Londdon, United Kingdom;(7)Western General Hospital, Department of Gastroenterology, Edinburgh, United Kingdom;(8)St George's University Hospitals NHS Foundation Trust, Department of Gastroenterology, London, United Kingdom;(9)Imperial College London, Department of Infectious Disease, London, United Kingdom;(10)Imperial College London, Department of Immunology and Inflammation, London, United Kingdom;CLARITY IBD
OP25: Prevalence of IBD in the Netherlands: development and validation of machine learning models for administrative dataECCO’23 CopenhagenYear: 2023
Authors: Van Linschoten, R.(1,2,3)*;van Leeuwen, N.(2);Hazelzet, J.A.(2);van der Woude, C.J.(3);van Noord, D.(4);West, R.L.(4);
(1)Franciscus Gasthuis & Vlietland, Gastroenterology & Hepatology, Rotterdam, The Netherlands;(2)Erasmus MC, Department of Public Health, Rotterdam, The Netherlands;(3)Erasmus MC, Department of Gastroenterology & Hepatology, Rotterdam, The Netherlands;(4)Franciscus Gasthuis & Vlietland, Department of Gastroenterology & Hepatology, Rotterdam, The Netherlands;
OP26: Impact of telemonitoring with TECCU on the management of Inflammatory Bowel Disease in Spain: a GETECCU clinical trialECCO’23 CopenhagenYear: 2023
Authors: Aguas Peris, M.(1,2)*;Del Hoyo, J.(1,2);Vicente, R.(3,4);Barreiro-de Acosta, M.(5);Melcarne, L.(6);Hernández-Camba, A.(7);Alfambra, E.(8,9);Madero, L.(10,11);Sicilia, B.(12);Chaparro, M.(13,14,15,16);Martín-Arranz, M.D.(14,17,18);Pajares, R.(19);Mesonero, F.(20);Mañosa, M.(16,21);Martínez, P.(22);Chacón , S.(23);Tosca, J.(24);Marín, S.(25,26);Sanromán, L.(27,28,29,30);Calvo, M.(31);Monfort, D.(32);Saiz, E.(33);Zabana, Y.(16,34);Guerra, I.(35);Varela, P.(36);Faubel, R.(37,38,39);Corsino, P.(3,4);Porto-Silva, S.(5);Brunet, E.(6);Gutiérrez, A.(10,11,16);Nos, P.(1,2);
(1)La Fe University and Polytechnic Hospital, Gastroenterology, Valencia, Spain;(2)Health Research Institute La Fe, IISLaFe, Valencia, Spain;(3)Miguel Servet University Hospital, Gastroenterology, Zaragoza, Spain;(4)Health Research Institute of Aragon, IIS Aragón, Zaragoza, Spain;(5)Santiago Clinic University Hospital, Gastroenterology, Santiago, Spain;(6)Parc Taulí Health Corporation, Gastroenterology, Sabadell, Spain;(7)Nuestra Señora de la Candelaria University Hospital, Gastroenterology, Tenerife, Spain;(8)Lozano Blesa Clinic University Hospital, Gastroenterology, Zaragoza, Spain;(9)IIS Aragón, Health Research Institute of Aragon IIS Aragon, Zaragoza, Spain;(10)Dr. Balmis General University Hospital, Gastroenterology, Alicante, Spain;(11)ISABIAL, Institute of Sanitary and Biomedical Research of Alicante, Alicante, Spain;(12)Burgos University Hospital, Gastroenterology, Burgos, Spain;(13)La Princesa University Hospital, Gastroenterology, Madrid, Spain;(14)Universidad Autónoma de Madrid, Faculty of Medicine, Madrid, Spain;(15)Princess Health Research Institute IIS-IP, IIS-La Princesa, Madrid, Spain;(16)Network Biomedical Research Center-ISCIII, CIBERehd, Madrid, Spain;(17)La Paz University Hospital, Gastroenterology, Madrid, Spain;(18)Investigación Sanitaria del Hospital Universitario La Paz, IdiPAZ, Madrid, Spain;(19)Infanta Sofía University Hospital, Gastroenterology, Madrid, Spain;(20)Ramón y Cajal University Hospital, Gastroenterology, Madrid, Spain;(21)Germans Trias i Pujol University Hospital-, Gastroenterology, Madrid, Spain;(22)San Cecilio Clinic University Hospital and Parque Tecnológico de la Salud, Gastroenterology, Granada, Spain;(23)Morales Meseguer General University Hospital, Gastroenterology, Murcia, Spain;(24)Clinic University Hospital, Gastroenterology, Valencia, Spain;(25)Reina Sofía University Hospital, Gastroenterology, Córdoba, Spain;(26)IMIBIC, Maimonides Institute for Biomedical Research of Córdoba, Córdoba, Spain;(27)Xerencia Xestion Integrada de Vigo-, Gastroenterology, Vigo, Spain;(28)IISGS, Galicia Sur Health Research Institute, Vigo, Spain;(29)Research Group in Digestive Diseases-, Digestive Diseases-, Vigo, Spain;(30)SERGAS, Galician Health Service, Vigo, Spain;(31)Puerta de Hierro University Hospital, Gastroenterology, Madrid, Spain;(32)Consorci Sanitari Terrasa-, Consorci Sanitari Terrasa-, Barcelona, Spain;(33)Xarxa Assistencial University Hospital, Gastroenterology, Manresa, Spain;(34)Mútua Terrassa University Hospital-, Gastroenterology, Barcelona, Spain;(35)Fuenlabrada University Hospital-, Gastroenterology, Fuenlabrada, Spain;(36)Cabueñes Universitary Hospital, Gastroenterology, Gijón, Spain;(37)ICT Applied to Reengineering Socio-Sanitary Process, Joint Research Unit, Valencia, Spain;(38)PTinMOTION-Physiotherapy in Motion Multispeciality Research Group- Universitat de València, Department of Physiotherapy, Valencia, Spain;(39)IIS La Fe-Universitat Politècnica de València, IISlaFe, Valencia, Spain;
OP27: Benefits of paediatric to adult transition program in Inflammatory Bowel Disease: The BUTTERFLY study of GETECCUECCO’23 CopenhagenYear: 2023
Authors: Rubín De Célix, C.(1)*;Martín de Carpi, J.(2);Pujol, G.(2);Palomino, L.(3);Velasco, M.(3);Martín-Masot, R.(4);Navas-López, V.M.(4);Ricart, E.(5);Casanova, M.J.(1);Rodríguez Martínez, A.(6);Leo, E.(7);Alcaraz, A.(8);Mañosa, M.(9);Hernández, V.(10);Fernández, R.(10);Sánchez, C.(11);Menchén, L.(12);Mesonero, F.(13);Barreiro-De Acosta, M.(14);Martinon, N.(15);Tejido Sandoval, C.(16);Rendo Vázquez, A.(17);Corsino, P.(18);Vicente, R.(18);Hernández-Camba, A.(19);Alberto Alonso, J.R.(20);Alonso-Abreu, I.(21);Castro Millán, A.M.(22);Peries Reverter, L.(23);Castro, B.(24);Fernández-Salgado, E.(25);Busto Cuiñas, M.M.(26);Benítez, J.M.(27);Madero, L.(28);Clemente, F.(29);Riestra, S.(30);Jiménez-Treviño, S.(31);Boscá, M.(32);Chaparro, M.(1);Gisbert, J.P.(1);
(1)Hospital Universitario de La Princesa, Gastroenterology Department. Instituto de Investigación Sanitaria Princesa IIS-Princesa- Universidad Autónoma de Madrid UAM- and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas CIBEREHD, Madrid, Spain;(2)Hospital Sant Joan de Déu, Paediatric Gastroenterology- Hepatology and Nutrition Unit, Barcelona, Spain;(3)Hospital Infantil Universitario Niño Jesús, Paediatric Gastroenterology and Nutrition Unit, Madrid, Spain;(4)Hospital Regional Universitario de Málaga, Paediatric Gastroenterology and Nutrition Unit, Málaga, Spain;(5)Hospital Clinic, Gastroenterology Department, Barcelona, Spain;(6)Hospital Universitario Virgen del Rocío, Paediatric Gastroenterology- Hepatology and Nutrition- UGC de Pediatría, Sevilla, Spain;(7)Hospital Virgen del Rocío, Gastroenterology Department, Sevilla, Spain;(8)University Hospital Germans Trias I Pujol, Department of Paediatric Gastroenterology- Nutrition and Hepatology, Badalona, Spain;(9)Hospital Universitari Germans Trias I Pujol and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas CIBEREHD, Gastroenterology Department, Badalona, Spain;(10)Xerencia Xestion Integrada de Vigo. SERGAS. Research Group in Digestive Diseases- Galicia Sur Health Research Institute IIS Galicia Sur. SERGAS-UVIGO, Department of Gastroenterology, Vigo, Spain;(11)Hospital General Universitario Gregorio Marañón, Paediatric Gastroenterology- Hepatology and Nutrition, Madrid, Spain;(12)Hospital General Universitario Gregorio Marañón, Gastroenterology Department – CEIMI. Departamento de Medicina- Universidad Complutense de Madrid, Madrid, Spain;(13)Hospital Universitario Ramón y Cajal, Gastroenterology Department, Madrid, Spain;(14)Hospital Universitario Clínico de Santiago, Gastroenterology Department, Santiago de Compostela, Spain;(15)Hospital Universitario Clínico de Santiago, Paediatric Gastroenterology- Hepatology and Nutrition Unit, Santiago de Compostela, Spain;(16)Complejo Hospitalario Universitario de Ourense, Gastroenterology Department, Orense, Spain;(17)Complejo Hospitalario Universitario de Ourense, Paediatric Gastroenterology- Hepatology and Nutrition Unit, Orense, Spain;(18)Hospital Universitario Miguel Servet, Inflammatory Bowel Disease Unit. Gastroenterology Department, Zaragoza, Spain;(19)Hospital Universitario Nuestra Señora de Candelaria, Gastroenterology Department, Santa Cruz de Tenerife, Spain;(20)Hospital Universitario Nuestra Señora de Candelaria, Paediatric Gastroenterology- Hepatology and Nutrition Unit, Santa Cruz de Tenerife, Spain;(21)Hospital Universitario de Canarias, Gastroenterology Department, Santa Cruz de Tenerife, Spain;(22)Hospital Universitario de Canarias, Paediatric Gastroenterology- Hepatology and Nutrition Unit, Santa Cruz de Tenerife, Spain;(23)Hospital Universitari de Girona Doctor Josep Trueta, Gastroenterology Department, Girona, Spain;(24)Hospital Universitario Marqués de Valdecilla, Gastroenterology Department, Santander, Spain;(25)Complejo Hospitalario Universitario de Pontevedra, Gastroenterology Department, Pontevedra, Spain;(26)Complejo Hospitalario Universitario de Pontevedra, Paediatric Gastroenterology- Hepatology and Nutrition Unit, Pontevedra, Spain;(27)Hospital Universitario Reina Sofía. IMIBIC, Gastroenterology Department, Córdoba, Spain;(28)Hospital Universitario de Alicante, Gastroenterology Department, Alicante, Spain;(29)Hospital Universitario de Alicante, Paediatric Gastroenterology- Hepatology and Nutrition Unit, Alicante, Spain;(30)Hospital Universitario Central de Asturias and Instituto de Investigación Sanitaria del Principado de Asturias ISPA, Gastroenterology Department, Oviedo, Spain;(31)Hospital Universitario Central de Asturias, Paediatric Gastroenterology and Nutrition Unit, Oviedo, Spain;(32)Hospital Clínico de Valencia, Gastroenterology Department, Valencia, Spain;On Behalf Of the BUTTERFLY Study Group of GETECCU
OP28: Children and young adults with inflammatory bowel disease have an increased incidence and risk of developing mental health conditions: a UK population-based cohort studyECCO’23 CopenhagenYear: 2023
Authors: Cooney, R.(1)*;Tang, D.(2);Barrett, K.(3);Russell, R.K.(4);
(1)Queen Elizabeth Hospital- Birmingham- UK, Department of Gastroenterology, Birmingham, United Kingdom;(2)Pfizer Ltd, Walton Oaks- Dorking Road, Tadworth, United Kingdom;(3)New Road Surgery, 166 New Road- Croxley Green, Rickmansworth, United Kingdom;(4)Royal Hospital for Children and Young People, Department of Paediatric Gastroenterology, Edinburgh, United Kingdom;
OP29: Peri-natal exposure to parental Crohn's disease is associated with impaired gut barrier, microbiome composition differences and increased risk of Crohn's diseaseECCO’23 CopenhagenYear: 2023
Authors: LeeDr., S.H.(1)*;Qiu, L.(1);A. Olivera, P.(1);Leibovitzh, H.(1);Xue, M.(1);Neustaeter, A.(1);Mbareche, H.(1);Xu, W.(2);Espin-Garcia, O.(2); L. Aumais, G.(3);Q. Huynh, H.(4);Panaccione, R.(5);Steinhart, A.H.(1);Cino, M.(6);Mack, D.(7);K. Marshall, J.(8);Ropeleski, M.(9);Bitton, A.(10);Jacobson, K.(11);McGraft, J.(12);Yerushalmi, B.(13);Abreu, M.(14);N. Bernstein, C.(15);Radford-Smith, G.(16);Lees, C.(17);Turner, D.(18);L. Madsen, K.(4);S. Guttman, D.(19);S. Silverberg, M.(1);Turpin, W.(1);Croitoru, K.(1);
(1)Mount Sinai Hospital- University of Toronto, Division of Gastroenterology, Toronto, Canada;(2)Dalla Lana School of Public Health- University of Toronto, Division of Biostatistics, Toronto, Canada;(3)Hopital Maisonneuve-Rosemont, Department of Gastroenterology, Montreal, Canada;(4)University of Alberta, Department of Gastroenterology, Edmonton, Canada;(5)University of Calgary, Department of Gastroenterology, Calgary, Canada;(6)University of Toronto, Division of Gastroenterology & Hepatology, Toronto, Canada;(7)Children's Hospital of Eastern Ontario- University of Ottawa, Division of Gastroenterology- Hepatology & Nutrition, Ottawa, Canada;(8)McMaster University, Farncombe Family Digestive Health Research Institute, Hamilton, Canada;(9)Queen's University, Gastrointestinal Diseases Research Unit, Kingston, Canada;(10)McGill University and McGill University Health Centre, Division of Gastroenterology and Hepatology, Montreal, Canada;(11)British Columbia Children's Hospital- University of British Columbia, Department of Pediatrics, Vancouver, Canada;(12)General Hospital- Health Sciences Centre, Department of Gastroenterology, St. John's, Canada;(13)Soroka University Medical Center and Faculty of Health Sciences- Ben-Gurion University of the Negev, Pediatric Gastroenterology Unit, Beer-Sheva, Israel;(14)University of Miami, Division of Gastroenterology- Department of Medicine, Miami, United States;(15)University of Manitoba, Inflammatory Bowel Disease Clinical and Research Centre, Winnipeg, Canada;(16)QIMR Berghofer Medical Research Institute, Department of Gastroenterology, Brisbane, Australia;(17)University of Edinburgh, Department of Gastroenterology, Edinburgh, United Kingdom;(18)Shaare Zedek Medical Center- The Hebrew University of Jerusalem, The Juliet Keidan Institute of Pediatric Gastroenterology and Nutrition, Jerusalem, Israel;(19)University of Toronto, Centre for the Analysis of Genome Evolution and Function, Toronto, Canada;Crohn's Colitis Canada Genetic Environmental Microbial (CCC-GEM) Project Research Team
OP30: Human umbilical cord mesenchymal stem cells derived exosomes alleviate Ulcerative Colitis by inhibiting macrophage ferroptosis via miR-23b-3p/Nrf2 pathwayECCO’23 CopenhagenYear: 2023
Authors: Liu, L.(1)*;Zhao, J.(1);Ye, Y.(1);Feng, Z.(1);Wang, X.(1);Cao, X.(1);
(1)Tianjin Medical University General Hospital, Department of Gastroenterology and Hepatology, Tianjin, China;
OP31: High fat diet exacerbates colitis through microbial metabolite deoxycholic acids induced-ferroptosisECCO’23 CopenhagenYear: 2023
Authors: Wang, C.(1)*;Gu, Y.(1);Cao, H.(1);
(1)Tianjin Medical University General Hospital, Department of Gastroenterology and Hepatology, Tianjin, China;
OP32: The gut virome-colonizing Orthohepadnavirus genus is associated with ulcerative colitis pathogenesis and induces intestinal inflammation in vivoECCO’23 CopenhagenYear: 2023
Authors: Facoetti, A.(1)*;Massimino, L.(2);Palmieri, O.(3);Fuggetta , D.(1);Spanò , S.(2);D'Alessio , S.(4);Furfaro, F.(5);D'Amico, F.(5);ZIlli, A.(5);Fiorino, G.(5);Noviello, D.(6);Latiano, A.(3);Bossa, F.(3);Pirola, A.(7);Mologni, L.(8);Piazza, R.(8);Abbati, D.(9);Perri, F.(3);Bonini , C.(9);Peyrin-Biroulet, L.(10);Malesci, A.(5);Danese, S.(5);Ungaro, F.(2);
(1)Università Vita-Salute San Raffaele, Department of Gastroenterology and Digestive Endoscopy in the Laboratory of Experimental Gastroenterology, Milan, Italy;(2)IRCCS Ospedale San Raffaele, Department of Gastroenterology and Digestive Endoscopy in the Laboratory of Experimental Gastroenterology, Milan, Italy;(3)Fondazione IRCCS Casa Sollievo della Sofferenza, Division of Gastroenterology, San Giovanni Rotondo FG, Italy;(4)Phoenix Lab, none, Lody, Italy;(5)IRCCS Ospedale San Raffaele, Department of Gastroenterology and Digestive Endcoscopy, Milan, Italy;(6)University of Milan, Department of Pathophysiology and Transplantation, Milan, Italy;(7)Galseq, None, Milan, Italy;(8)University of Milano - Bicocca, Department of Medicine and Surgery, Monza, Italy;(9)IRCCS Ospedale San Raffaele, Division of Immunology- Transplantation and Infectious Disease, Milan, Italy;(10)Inserm NGERE, University of Lorraine, Nancy, France;
OP33: Results of a randomised controlled trial to evaluate Interleukin 1 blockade with anakinra in patients with acute severe ulcerative colitis (IASO)ECCO’23 CopenhagenYear: 2023
Authors: Raine, T.(1)*;Vaja, S.(2);Subramanian, S.(1);Brezina, B.(1);Probert, C.S.(3);Steel, A.(3);Lofthouse, M.(3);Speight, R.A.(4);Lamb, C.(4);Sebastian, S.(5);Kane, J.(5);Thut, J.(5);Din, S.(6);Arnott, I.(6);Smith, L.(6);Galea, J.(7);Hendy, P.(8);Flores, L.(9);Selinger, C.(10);Onoviran, F.(10);Steed, H.(11);Green, M.(12);Williams, J.(13);Jairath, V.(14);Qian, W.(2);Pavey, H.(2);Champion, K.(2);Dowling, F.(2);Thomas, M.(2);Wolf, K.(2);Davis-Wilkie, C.(2);Parkes, M.(1);Kaser, A.(15);
(1)Cambridge University Hospitals NHS Foundation Trust, Department of Gastroenterology, Cambridge, United Kingdom;(2)Cambridge University Hospitals NHS Foundation Trust, Cambridge Clinical Trials Unit, Cambridge, United Kingdom;(3)Royal Liverpool University Hospital, Department of Gastroenterology, Liverpool, United Kingdom;(4)Royal Victoria Infirmary, Department of Gastroenterology, Newcastle, United Kingdom;(5)Hull University Teaching Hospitals, IBD Unit, Hull, United Kingdom;(6)Western General Hospital- NHS Lothian, IBD Unit, Edinburgh, United Kingdom;(7)Cardiff and Vale University Health Board- Cardiff, Neurosurgery, Cardiff, United Kingdom;(8)Chelsea and Westminster NHS Trust, Department of Gastroenterology, London, United Kingdom;(9)Chelsea and Westminster NHS Trust, Research and Development, London, United Kingdom;(10)St James University Hospital, Department of Gastroenterology, Leeds, United Kingdom;(11)University of Wolverhampton, Department of Gastroenterology, Wolverhampton, United Kingdom;(12)The Royal Wolverhampton NHS Trust, Department of Gastroenterology, Wolverhampton, United Kingdom;(13)Swansea University, Department of Medicine, Swansea, United Kingdom;(14)Western University, Department of Gastroenterology, London, Canada;(15)University of Cambridge, Department of Medicine, Cambridge, United Kingdom;The IASO trial investigators
OP34: Enteral Nutrition Compared with Steroids in Children with Crohn's Disease – In Israel: a nationwide study from the epi-IIRNECCO’23 CopenhagenYear: 2023
Authors: Plotkin, L.(1)*;Lujan, R.(1);Focht, G.(1);Greenfeld, S.(2);Loewenberg Weisband, Y.(3);Lederman, N.(4);Matz, E.(5);Dotan, I.(6);Turner, D.(1);
(1)Juliet Keidan Institute of Pediatric Gastroenterology Hepatology and Nutrition, Shaare Zedek Medical Center- The Hebrew University of Jerusalem- Israel, Jerusalem, Israel;(2)Maccabi Health Services and the Sackler Faculty of Medicine, Tel Aviv University, Tel-Aviv, Israel;(3)Clalit Health Services, Clalit Research Institute- Tel-Aviv- Israel, Tel-Aviv, Israel;(4)Meuhedet Health Services, Meuhedet Health Services, Tel-Aviv, Israel;(5)Leumit Health Services, Leumit Health Services, Tel-Aviv, Israel;(6)Division of Gastroenterology- Rabin Medical Center- Petah Tikva, and the Sackler Faculty of Medicine- Tel Aviv University, Tel-Aviv, Israel;
OP35: Efficacy and safety outcomes up to ~4 years of treatment with filgotinib 200 mg among patients with Ulcerative Colitis: Results from the SELECTIONLTE studyECCO’23 CopenhagenYear: 2023
Authors: FeaganSenior Scientific Officer, B.G.(1)*;Matsuoka, K.(2);Rogler, G.(3);Faes, M.(4);Oortwijn, A.(5);de Haas, A.(6);Rudolph, C.(5);Peyrin-Biroulet, L.(7);
(1)Alimentiv Inc., Division of Gastroenterology, London, Canada;(2)Toho University Sakura Medical Center, Department of Gastroenterology and Hepatology, Chiba, Japan;(3)University Hospital Zurich, Department of Gastroenterology and Hepatology, Zurich, Sweden;(4)Galapagos NV, Biostatistics Department, Mechelen, Belgium;(5)Galapagos NV, Medical Affairs Department, Leiden, The Netherlands;(6)Galapagos NV, Clinical Development Department, Leiden, The Netherlands;(7)University Hospital of Nancy- University of Lorraine, Department of Gastroenterology, Vandoeuvre-lès-Nancy, France;
OP36: Real-world evidence on comparative effectiveness of Ustekinumab vs anti-TNF in Crohn's disease with propensity score adjustment: two-year maintenance phase results from the prospective observational RUN-CD studyECCO’23 CopenhagenYear: 2023
Authors: Bokemeyer, B.(1,2,3)*;Plachta-Danielzik, S.(3);Deppe, H.(4);Mohl, W.(5);Teich, N.(6);Hoffstadt, M.(7);Schweitzer, A.(8);von der Ohe, M.(9);Gauss, A.(10);Atreya, R.(11);Krause, T.(12);Blumenstein, I.(13);Fajardo Salmon, S.(3);Hartmann, P.(4);Gilman, E.(3);Schreiber, S.(3,14);
(1)Prof. Dr. Bernd Bokemeyer, Interdisciplinary Crohn Colitis Centre Minden, Minden, Germany;(2)University Hospital Schleswig-Holstein- Campus Kiel, Clinic for General Internal Medicine I, Kiel, Germany;(3)Competence Network IBD, Study Department, Kiel, Germany;(4)Gastroenterology Practice Minden, Gastroenterology, Minden, Germany;(5)Centre for Gastroenterology Saar MVZ, Gastroenterology, Saarbrücken, Germany;(6)Gastroenterology Practice Leipzig, Gastroenterology, Leipzig, Germany;(7)Gastroenterology Practice Iserlohn, Gastroenterology, Iserlohn, Germany;(8)Gastroenterology Practice Münster, Gastroenterology, Münster, Germany;(9)Gastroenterology Practice Herne, Gastroenterology, Herne, Germany;(10)University Hospital Heidelberg, Department Internal Medicine IV - Gastroenterology Clinic, Heidelberg, Germany;(11)Friedrich-Alexander-University Erlangen-Nürnberg, Medical Clinic 1, Erlangen, Germany;(12)Gastroenterology Practice Kassel, Gastroenterology, Kassel, Germany;(13)Johann Wolfgang Goethe University Clinic Frankfurt, Department of Gastroenterology and Clinical Nutrition, Frankfurt, Germany;(14)University Hospital Schleswig-Holstein Campus Kiel, Clinic of General Internal Medicine I, Kiel, Germany;
OP37: Is the withdrawal of anti-tumour necrosis factor in inflammatory bowel disease patients in remission feasible without increasing the risk of relapse? Results from the randomised clinical trial of GETECCU (EXIT)ECCO’23 CopenhagenYear: 2023
Authors: Chaparro, M.(1)*;García Donday, M.(1);Riestra, S.(2);Lucendo, A.J.(3);Benítez, J.M.(4);Navarro-Llavat, M.(5);Barrio, J.(6);Morales-Alvarado, V.J.(7);Rivero, M.(8);Busquets, D.(9);Leo Carnerero, E.(10);Merino Ochoa, O.(11);Nantes Castillejo, O.(12);Navarro, P.(13);Van Domselaar, M.(14);Gutiérrez Casbas, A.(15);Alonso-Abreu, I.(16);Mejuto, R.(17);Fernández Salazar, L.(18);Iborra, M.(19); Martín-Arranz, M.D.(20); Pineda, J.R.(21); Sampedro, M.J.(22);Serra Nilsson, K.(23);Bouhmidi Assakali, A.(24);Batista, L.(25);Muñoz Villafranca, C.(26);Rodríguez-Lago, I.(27); Ceballos Santos, D.S.(28);Guerra, I.(29);Mañosa, M.(30);Marín Jimenez, I.(31); Vera Mendoza, I.(32);Barreiro-de Acosta, M.(17);Domènech, E.(30);Esteve, M.(25);García-Sánchez, V.(4);Nos, P.(19);Panés, J.(33);Gisbert, J.P.(1);
(1)Hospital Universitario de La Princesa- IIS-Princesa- Universidad Autónoma de Madrid UAM- and CIBEREHD, Gastroenterology Unit, Madrid, Spain;(2)Hospital Universitario Central de Asturias and Instituto de Investigación Sanitaria del Principado de Asturias ISPA, Gastroenterology Unit, Oviedo, Spain;(3)Hospital General de Tomelloso- CIBERehd and Instituto de Investigación Sanitaria de Castilla-La Mancha IDISCAM, Gastroenterology Unit, Tomelloso, Spain;(4)Hospital universitario Reina Sofía and IMIBIC, Gastroenterology Unit, Córdoba, Spain;(5)Hospital de Sant Joan Despí Moisès Broggi, Gastroenterology Unit, Barcelona, Spain;(6)Hospital Universitario Río Hortega- Gerencia Regional de Salud de Castilla y León SACYL, Gastroenterology Unit, Valladolid, Spain;(7)Hospital General de Granollers, Gastroenterology Unit, Granollers, Spain;(8)Hospital Universitario Marqués de Valdecilla and IDIVAL, Gastroenterology Unit, Santander, Spain;(9)Hospital Universitari Dr. Josep Trueta, Gastroenterology Unit, Girona, Spain;(10)Hospital Universitario Virgen del Rocío, Gastroenterology Unit, Sevilla, Spain;(11)Hospital Universitario de Cruces, Gastroenterology Unit, Baracaldo, Spain;(12)Hospital Universitario de Navarra, Gastroenterology Unit, Pamplona, Spain;(13)Hospital Clínico Universitario de Valencia, Gastroenterology Unit, Valencia, Spain;(14)Hospital Universitario de Torrejón and Universidad Francisco de Vitoria, Gastroenterology Unit, Madrid, Spain;(15)Hospital General Universitario Dr Balmis- ISABIAL and CIBERehd, Gastroenterology Unit, Alicante, Spain;(16)Hospital Universitario de Canarias, Gastroenterology Unit, Santa Cruz de Tenerife, Spain;(17)Complexo Hospitalario Universitario de Santiago de Compostela, Gastroenterology Unit, Santiago de Compostela, Spain;(18)Hospital Clínico Universitario de Valladolid and Universidad de Valladolid, Gastroenterology Unit, Valladolid, Spain;(19)Hospital Universitari y Politecnic La Fe, Gastroenterology Unit, Valencia, Spain;(20)Hospital Universitario La Paz- Facultad de Medicina- Universidad Autónoma de Madrid and Instituto de Investigación Hospital universitario La Paz IdiPAZ, Gastroenterology Unit, Madrid, Spain;(21)Xerencia Xestión Integrada de Vigo- SERGAS- Research Group In Digestive Diseases- Galicia Sur Health Research Institute- SERGAS-UVIGO, Gastroenterology Unit, Vigo, Spain;(22)Hospital de Mataró, Gastroenterology Unit, Barcelona, Spain;(23)Hospital Universitari de Bellvitge, Gastroenterology Unit, L'Hospitalet de Llobregat, Spain;(24)Hospital de Santa Bárbara, Gastroenterology Unit, Puertollano, Spain;(25)Hospital Universitari Mutua Terrassa and CIBEREHD, Gastroenterology Unit, Barcelona, Spain;(26)Hospital Universitario de Basurto, Gastroenterology Unit, Bilbao, Spain;(27)Hospital Universitario de Galdakao and Instituto de Investigación Sanitaria Biocruces de Bizkaia, Gastroenterology Unit, Galdakao, Spain;(28)Hospital Universitario de Gran Canaria Dr. Negrín, Gastroenterology Unit, Las Palmas de Gran Canaria, Spain;(29)Hospital Universitario de Fuenlabrada and Instituto de Investigación Hospital Universitario La Paz IdiPAZ, Gastroenterology Unit, Madrid, Spain;(30)Hospital Universitari Germans Trias i Pujol and CIBEREHD, Gastroenterology Unit, Badalona, Spain;(31)Hospital Gregorio Marañón- Instituto de Investigación Sanitaria Gregorio Marañón IiSGM- Facultad de Medicina- Universidad Complutense, Gastroenterology Unit, Madrid, Spain;(32)Hospital Universitario Puerta de Hierro, Gastroenterology Unit, Majadahonda, Spain;(33)Hospital Clinic y Provincial, Gastroenterology Unit, Barcelona, Spain;on behalf of the EXIT Study group of GETECCU
OP38: Modulation of the septin cytoskeleton ameliorates intestinal fibrogenesisECCO’23 CopenhagenYear: 2023
Authors: Naydenov, N.(1);Le, T.H.N.(1);Lechuga Villarauz, S.(1);Elias, M.(1);West, G.(1);Czarnecki, D.(1);Plesec, T.(1);Ivanov, A.(1);Rieder, F.(2)*;
(1)Cleveland Clinic, Inflammation and Immunity, Cleveland, United States;(2)Cleveland Clinic, Department of Gastroenterology- Hepatology and Nutrition, Cleveland, United States;
OP39: Safety of ustekinumab in IBD: Final pooled long-term safety analysis through 5 years in CD and 4 years in UCECCO’23 CopenhagenYear: 2023
Authors: Ghosh, S.(1)*;Feagan, B.(2);Ott, E.(3);Gasink, C.(3);Marano, C.(4);Miao, Y.(4);Sandborn, W.(5);Danese, S.(6);Abreu, M.(7);Sands, B.(8);
(1)University College Cork, College of Medicine and Health, Cork, Ireland;(2)Western University and Alimentiv Inc., Gastroenterology, London, Canada;(3)Janssen, Scientific Affairs, Horsham, United States;(4)Janssen, Research & Development, Spring House, United States;(5)University of California San Diego, Division of Gastroenterology, La Jolla, United States;(6)IRCCS Ospedale San Raffaele and University Vita-Salute San Raffaele, Gastroenterology and Endoscopy, Milano, Italy;(7)University of Miami, Miller School of Medicine, Miami, United States;(8)Icahn School of Medicine at Mount Sinai, Dr. Henry D. Janowitz Division of Gastroenterology, New York, United States;