DOP65: T-cell derived TGFβ1 remodels the rectum mesenchyme in Crohn's Disease patients with perianal fistulizing diseaseECCO’23 CopenhagenYear: 2023
Authors: Gudiño, V.(1)*;Cho, J.W.(2);Corraliza, A.M.(1);Caballol, B.(3);Garrido-Trigo, A.(1);Masamunt, M.C.(3);Ordás, I.(3);Ricart, E.(3);Hemberg, M.(2);Panés, J.(3);Salas, A.(1);
(1)Institut d'Investigacions Biomèdiques August Pi i Sunyer IDIBAPS, Inflammatory Bowel Disease Unit, Barcelona, Spain;(2)Evergrande Centre- Brigham and Women's Hospital, Quantitative models of gene expression, Boston, United States;(3)Hospital Clinic, Inflammatory Bowel Disease Unit, Barcelona, Spain;
DOP66: Ileal resections from fibrotic-CD patients present microbiota dysbiosis, altered metabolomic profiles and metabolite-sensing GPCRs expressionECCO’23 CopenhagenYear: 2023
Authors: Bauset, C.(1)*;Carda-Diéguez, M.(2);Buetas, E.(2);Lis-López, L.(1);Seco-Cervera, M.(3);Coll, S.(1);Ortiz-Masiá, D.(4);Calatayud, S.(5);Barrachina, M.D.(5);Mira, Á.(6);Cosín-Roger, J.(3);
(1)Universitat de València, Pharmacology, València, Spain;(2)FISABIO, Genomics and Health, València, Spain;(3)Universitat de València-FISABIO, Pharmacology, València, Spain;(4)Universitat de València-CIBERehd, Medicine, València, Spain;(5)Universitat de València-CIBERehd, Pharmacology, València, Spain;(6)FISABIO-CIBERESP, Genomics and Health, València, Spain;
DOP68: Autophagy induction in the intestinal epithelium protects against inflammation-induced barrier loss in vivo.ECCO’23 CopenhagenYear: 2023
Authors: Saha, K.(1)*;Ganapathy, A.S.(1);Wang, A.(1);Morris, N.(1);Yochum, G.(2);Koltun, W.(2);Ding, W.(2);Nighot, M.(1);Ma, T.(1);Nighot, P.(1);
(1)Penn State College of Medicine, Medicine, Hershey, United States;(2)Penn State College of Medicine, Surgery, Hershey, United States;
DOP69: Glycans as an actor in the microbiome-immune response crosstalk.ECCO’23 CopenhagenYear: 2023
Authors: Rodrigues, C.(1);Gaifem, J.(2);Pereira, M.(2);Lavelle, A.(3);Colombel, J.F.(4);Sokol, H.(5);Pinho, S.(6)*;
(1)ICBAS- School of Medicine and Biomedical Sciences and i3S - University of Porto, Immunology- Cancer & GlycoMedicine, Porto, Portugal;(2)i3S - University of Porto, Immunology- Cancer & GlycoMedicine, Porto, Portugal;(3)Sorbonne University, Na, Paris, France;(4)Icahn School of Medicine Mount Sinai, Na, New York, United States;(5)Saint-Antoine Hospital, Na, Paris, France;(6)i3S-University of Porto, Immunology- Cancer andGlycoMedicine group, Porto, Portugal;
DOP70: Crohn's Disease Like Inflammation of The Pouch is a Distinct Type of PouchitisECCO’23 CopenhagenYear: 2023
Authors: Kayal, M.(1)*;Tankelevich, M.(2);Guo, Y.(3);Fischer, J.(4);Jimenez, D.(5);Canales-Herrerias, P.(2);Livanos, A.(2);Colombel, J.F.(1);Dubinsky, M.(6);Faith, J.(4);Ko, H.(3);Mehandru, S.(2);
(1)Icahn School of Medicine at Mount Sinai, Medicine/Gastroenterology, New York, United States;(2)Icahn School of Medicine at Mount Sinai, Gastroenterology/Immunology, New York, United States;(3)Columbia University Medical Center, Pathology, New York, United States;(4)Icahn School of Medicine at Mount Sinai, Genetics and Genomic Sciences, New York, United States;(5)Icahn School of Medicine at Mount Sinai, Gastroenterology, New York, United States;(6)Icahn School of Medicine at Mount Sinai, Pediatrics/Gastroenterology, New York, United States;
DOP71: TREM1, OSM and a co-expressed transcriptional module are core components of the molecular resistome to anti-cytokine therapy in Ulcerative ColitisECCO’23 CopenhagenYear: 2023
Authors: Saifuddin, A.(1)*;Madgwick, M.(2);Cozzetto, D.(1);Pavlidis, P.(3);Verstockt, B.(4,5);Hart, A.(1,6);Korcsmaros, T.(1);Powell, N.(1);
(1)Imperial College London, Department of Metabolism- Digestion and Reproduction, London, United Kingdom;(2)Earlham Institute, Organisms and Ecosystems, Norwich, United Kingdom;(3)King's College Hospital NHS Trust, Department of Gastroenterology, London, United Kingdom;(4)University Hospitals Leuven, Department of Gastroenterology and Hepatology, Leuven, Belgium;(5)KU Leuven, Department of Chronic Diseases and Metabolism, Leuven, United Kingdom;(6)St Mark's Academic Institute, Department of Gastroenterology, London, United Kingdom;
DOP73: Predicting endoscopic improvement in Ulcerative Colitis using the Ulcerative Colitis Severity Index (UCSI)ECCO’23 CopenhagenYear: 2023
Authors: Wong, E.C.L.(1);Dulai, P.S.(2);Marshall, J.K.(1);Jairath, V.(3);Reinisch, W.(4);Narula, N.(1)*;
(1)McMaster University, Department of Medicine Division of Gastroenterology and Farncombe Family Digestive Health Research Institute, Hamilton, Canada;(2)Northwestern University, Division of Gastroenterology, Chicago, United States;(3)Western University, Department of Medicine Division of Gastroenterology, London, Canada;(4)Medical University of Vienna, Department of Internal Medicine III Division of Gastroenterology and Hepatology, Vienna, Austria;
DOP74: Artificial Intelligence Quantifying Endoscopic Severity of Ulcerative Colitis in Gradation ScaleECCO’23 CopenhagenYear: 2023
Authors: Takabayashi, K.(1)*;Kobayashi, T.(2);Matsuoka, K.(3);G Levesque, B.(4);Kawamura, T.(5);Tanaka, K.(5);Kadota, T.(6);Bise, R.(6);Uchida, S.(6);Kanai, T.(7);Ogata, H.(1);
(1)School of Medicine- Keio University, Center for Diagnostic and Therapeutic Endoscopy, Tokyo, Japan;(2)Kitasato University Kitasato Institute Hospital, Center for Advanced IBD Research and Treatment, Tokyo, Japan;(3)Toho University Sakura Medical Center, Division of Gastroenterology and Hepatology, Tokyo, Japan;(4)Los Angeles County/University of Southern California Medical Center, Division of Gastroenterology, Los Angeles, United States;(5)Kyoto Second Red Cross Hospital, Department of Gastroenterology, Kyoto, Japan;(6)Kyushu University, Department of Advanced Information Technology, Fukuoka, Japan;(7)School of Medicine- Keio University, Division of Gastroenterology and Hepatology Department of Internal Medicine, Tokyo, Japan;
DOP75: Video capsule endoscopy may detect active small bowel Crohn's disease requiring change of treatment despite unremarkable ileo-colonic anastomosisECCO’23 CopenhagenYear: 2023
Authors: Thurm, T.(1,2)*;Zmora, N.(1,2,3);Hirsh, A.(1,2);Deutsch, L.(1,2);Maharshak, N.(1,2);
(1)Tel-Aviv Sourasky Medical Center, Department of Gastroenterology and Liver Diseases, Tel-Aviv, Israel;(2)Tel-Aviv University, Sackler School of Medicine, Tel-Aviv, Israel;(3)Weizmann Institute of Science, Immunology Department, Rehovot, Israel;
DOP76: Comparison of healing of complex perianal Crohn´s disease fistulas by advancement flap and mesenchymal stem cell therapyECCO’23 CopenhagenYear: 2023
Authors: Serclova, Z.(1)*;Tremerova, A.(2);Lengalova, M.(2);Petra, Z.(1);
(1)NH Hospital, Surgical Department, Horovice, Czech Republic;(2)NH Hospital, Surgical Departement, Horovice, Czech Republic;
DOP77: Is durable remission achievable after ileocolic resection for Crohn's disease ? Long-term results of a prospective multicentric cohort study of the GETAID ChirurgieECCO’23 CopenhagenYear: 2023
Authors: Abdalla, S.(1)*;Benoist, S.(1);Maggiori, L.(2);Lefevre, J.(3);Denost, Q.(4);Cotte, E.(5);Germain, A.(6);Beyer-Berjot, L.(7);Desfourneaux, V.(8);Rahili, A.(9);Duffas, J.P.(10);Pautrat, K.(11);Denet, C.(12);Bridoux, V.(13);Meurette, G.(14);Faucheron, J.L.(15);Loriau, J.(16);Souche, F.R.(17);Corte, H.(2);Zerbib, P.(18);Panis, Y.(19);Brouquet, A.(1);
(1)Le Kremlin-Bicetre University Hospital, Department of Digestive Surgery, Le Kremlin-Bicetre, France;(2)Saint-Louis University Hospital, Department of Digestive Surgery, Paris, France;(3)Saint-Antoine Hospital, Department of Digestive Surgery, Paris, France;(4)Bordeaux University Hospital, DEpartment of Digestive Surgery, Bordeaux, France;(5)Lyon-Sud University Hospital, Department of Digestive Surgery, Pierre-Benite, France;(6)Nancy University Hospital, Department of Digestive Surgery, Nancy, France;(7)Marseille University Hospital, Department of Digestive Surgery, Marseille, France;(8)Rennes University Hospital, Department of Digestive Surgery, Rennes, France;(9)Nice University Hospital, Department of Digestive Surgery, Nice, France;(10)Toulouse University Hospital, Department of Digestive Surgery, Toulouse, France;(11)Lariboisière University Hospital, Department of Digestive Surgery, Paris, France;(12)Institut Mutualiste Montsouris, Department of Digestive SUrgery, Paris, France;(13)Rouen University Hospital, Department of Digestive Surgery, Rouen, France;(14)Nantes University Hospital, Department of Digestive Surgery, Nantes, France;(15)Grenoble University Hospital, Department of Digestive Surgery, Grenoble, France;(16)Saint-Joseph Hospital, Department of Digestive Surgery, Paris, France;(17)Montpellier University Hospital, Department of Digestive Surgery, Montpellier, France;(18)Lille University Hospital, Department of Digestive Surgery, Lille, France;(19)Beaujon University Hospital, Department of Digestive Surgery, Clichy, France;GETAID Chirurgie
DOP78: Does KONO-S anastomosis reduce recurrence in Crohn's disease compared to conventional ileocolonic anastomosis ? A nationwide propensity score-matched study from GETAID Chirurgie Group (KoCoRICCO study).ECCO’23 CopenhagenYear: 2023
Authors: Alibert, L.(1);Betton, L.(2);Falcoz, A.(3);Manceau, G.(4);Benoist, S.(5);Zerbib, P.(6);Podevin, J.(7);Maggiori, L.(8);Brouquet, A.(5);Tyrode, G.(9);Vuitton, L.(9);Vernerey, D.(3);Lefevre, J.(2);Lakkis, Z.(1)*;
(1)University Hospital of Besançon, Department of Digestive Surgery, Besançon, France;(2)St Antoine Hospital, Department of Digestive Surgery, Paris, France;(3)University Hospital of Besançon, Methodology and Quality of Life Unit in Oncology, Besançon, France;(4)European Georges Pompidou Hospital, Department of Digestive and Oncologic Surgery, Paris, France;(5)Bicêtre Hospital, Department of Digestive Surgery and Surgical Oncology, Le Kremlin Bicêtre, France;(6)Lille University Hospital, Department of Digestive Surgery and Transplantation, Lille, France;(7)University Hospital of Nantes, Digestive and Endocrine Surgery Clinic, Nantes, France;(8)St Louis Hospital, Department of General- Endocrine and Digestive Surgery, Paris, France;(9)University Hospital of Besançon, Department of Gastroenterology, Besançon, France;GETAID Chirurgie
DOP79: Alternative polygenic forms of Inflammatory Bowel Disease are not captured by current generations of polygenic risk scoresECCO’23 CopenhagenYear: 2023
Authors: Mateos, B.(1)*;Gaite, A.(1);Rodríguez-Lago, I.(2);M. Marigorta, U.(1);
(1)cic bioGUNE, Integrative Genomics, Bilbao, Spain;(2)Galdakao Hospital, Gastroenterology, Bilbao, Spain;
DOP80: Multi-omic sequencing reveals distinctive gene expression and DNA methylation alterations as potential predictors of primary sclerosing cholangitis development in treatment-naïve paediatric ulcerative colitisECCO’23 CopenhagenYear: 2023
Authors: Lawal, O.(1)*;Rodriguez-Sosa, A.(1);McDonnell, C.(1);Grant, L.(1);O'Brien, J.(2);Kel, A.(3);Dominik, A.(4);Stack, R.(5);Yochum, G.(6,7);Koltun, W.(6);Doherty, G.(5);Hussey, S.(8);
(1)Royal College of Surgeons in Ireland, School of Pharmacy and Biomolecular Sciences, Dublin, Ireland;(2)Children's Health Ireland- Crumlin, Department of Pathology, Dublin, Ireland;(3)GeneXplain GmbH, GeneXplain GmbH, Wolfenbüttel, Germany;(4)Children's Health Ireland- Crumlin, DOCHAS Study, Dublin, Ireland;(5)St. Vincent's University Hospital and University College, Center for Colorectal Disease, Dublin, Ireland;(6)The Pennsylvania State University- College of Medicine- PA, Department of Surgery- Division of Colon and Rectal Surgery, Pennsylvania, United States;(7)The Pennsylvania State University- College of Medicine- PA, Department of Biochemistry & Molecular Biology, Pennsylvania, United States;(8)UCD and Royal College of Surgeons in Ireland, Department of Paediatrics, Dublin, Ireland;
DOP81: Unaffected ileal transcriptomics in Crohn's disease is associated with the response to anti-TNF therapyECCO’23 CopenhagenYear: 2023
Authors: Lee, H.S.(1)*;Lee, Y.(1);Baek, J.(1);Kim, Y.(1);Park, S.(1);Jung, S.(1);Kim, K.K.(2);Hwang, S.W.(2);Lee, J.L.(3);Park, S.H.(2);Yang, S.K.(2);Han, B.(4);Song, K.(1);Yoon, Y.S.(3);Ye, B.D.(2);
(1)University of Ulsan College of Medicine, Department of Biochemistry and Molecular Biology, Seoul, Korea- Republic Of;(2)University of Ulsan College of Medicine- Asan Medical Center, Department of Gastroenterology, Seoul, Korea- Republic Of;(3)University of Ulsan College of Medicine- Asan Medical Center, Department of Surgery, Seoul, Korea- Republic Of;(4)Seoul National University College of Medicine, Department of Biomedical Sciences, Seoul, Korea- Republic Of;
DOP82: Biological Treatment Cycles in Crohn's DiseaseECCO’23 CopenhagenYear: 2023
Authors: Noor, N.(1)*;Sousa, P.(2);Bettenworth, D.(3);Gomollon, F.(4);Lobaton, T.(5,6);Bossuyt, P.(7);Casanova, M.J.(8);Ding, N.(9);Dragoni, G.(10,11);Furfaro, F.(12);van Rheenen, P.(13);Chaparro, M.(8);Gisbert, J.(8);Louis, E.(14);Papamichael, K.(15);
(1)Addenbrooke's Hospital- Cambridge University Hospitals NHS Foundation Trust, Department of Gastroenterology, Cambridge, United Kingdom;(2)Viseu Unit- Tondela-Viseu Hospital Centre, Department of Gastroenterology, Viseu, Portugal;(3)University of Münster, Medical Faculty of the University of Münster, Münster, Germany;(4)Hospital Clínico Universitario Lozano Blesa, Department of Gastroenterology, Zaragoza, Spain;(5)University Hospital Ghent, Department of Gastroenterology, Ghent, Belgium;(6)Ghent University, Department of Internal Medicine and Pediatrics, Ghent, Belgium;(7)Imelda GI Clinical Research Centre, Department of Gastroenterology, Bonheiden, Belgium;(8)Instituto de Investigación Sanitaria Princesa IIS-Princesa- Universidad Autónoma de Madrid UAM- Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas CIBERehd, Gastroenterology Unit- Hospital Universitario de La Princesa, Madrid, Spain;(9)University of Melbourne- St Vincent's Hospital, Department of Gastroenterology, Melbourne, Australia;(10)University of Florence, Department of Experimental and Clinical Biomedical Sciences 'Mario Serio'- Gastroenterology Research Unit, Florence, Italy;(11)Careggi University Hospital, IBD Referral Center- Gastroenterology Department, Florence, Italy;(12)IRCCS San Raffaele Hospital, Department of Gastroenterology and Endoscopy, Milan, Italy;(13)University Medical Center Groningen, Department of Paediatric Gastroenterology, Groningen, The Netherlands;(14)Liege University Hospital- CHU Liege, Department of Hepato-Gastroenterology and Digestive Oncology, Liege, Belgium;(15)Beth-Israel Deaconess Medical Center- Harvard Medical School, Center for Inflammatory Bowel Diseases- Division of Gastroenterology, Boston, United States;
DOP83: Proactive dosing is superior to clinically based dosing in terms of endoscopic healing in paediatric patients with Crohn's disease receiving maintenance infliximab: A randomized controlled trialECCO’23 CopenhagenYear: 2023
Authors: Kang, B.(1)*;Moon, J.S.(2);Lee, Y.J.(3);Kim, M.J.(4);Choe, B.H.(1);Ko, J.S.(2);Park, J.H.(3);Choe, Y.H.(4);
(1)Kyungpook National University School of Medicine, Department of Pediatrics, Daegu, Korea- Republic Of;(2)Seoul National University College of Medicine, Department of Pediatrics, Seoul, Korea- Republic Of;(3)Pusan National University College of Medicine, Department of Pediatrics, Yangsan, Korea- Republic Of;(4)Sungkyunkwan University School of Medicine, Department of Pediatrics, Seoul, Korea- Republic Of;
DOP84: IBD-related hospitalization and surgery rates in biologic-naïve patients with IBD treated with vedolizumab versus other biologics: Results from a long-term, prospective, observational studyECCO’23 CopenhagenYear: 2023
Authors: Sebastian, S.(1)*;Siegel, C.(2);Siegmund, B.(3);Zhou, J.(4);Jones, S.(5);Adsul, S.(4);Louis, E.(6);
(1)Hull University Teaching Hospital, IBD Unit, Hull, United Kingdom;(2)Dartmouth Hitchcock Medical Center, Gastroenterology and Hepatology, Lebanon, United States;(3)Charité–Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany;(4)Takeda, Gastroenterology, Cambridge- MA, United States;(5)Takeda, Gastroenterology, Zurich, Switzerland;(6)University Hospital CHU of Liège, Department of Gastroenterology, Liège, Belgium;
