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OP24: Neutralising antibody potency against SARS-CoV-2 wild-type and Omicron BA.1 and BA.4/5 variants in infliximab and vedolizumab treated patients with Inflammatory Bowel Disease after three doses of COVID-19 vaccine: a prospective multicentre cohort studyECCO’23 Copenhagen
Year: 2023
Authors: Liu, Z.(1)*;Le, K.(1);Zhou, X.(1);Alexander, J.(1);Lin, S.(2);Bewshea, C.(2);Chanchlani, N.(2);Nice, R.(3);McDonald, T.(3);Lamb, C.(4);Sebastian, S.(5);Kok, K.(6);Lees, C.(7);Hart, A.(1);Pollok, R.(8);Boyton, R.(9);Altmann, D.(10);Pollock, K.(9);Goodhand, J.(2);Kennedy, N.(2);Ahmad, T.(2);Powell, N.(1);
(1)Imperial College London, Department of Metabolism Digestion and Reproduction, London, United Kingdom;(2)Royal Devon University Healthcare NHS Foundation Trust, Department of Gastroenterology, Exeter, United Kingdom;(3)Royal Devon University Healthcare NHS Foundation Trust, Department of Biochemistry, Exeter, United Kingdom;(4)Newcastle upon Tyne Hospitals NHS Foundation Trust, Department of Gastroenterology, Newcastle, United Kingdom;(5)Hull University Teaching Hospitals NHS Trust, Department of Gastroenterology, Hull, United Kingdom;(6)Barts Health NHS Trust, Department of Gastroenterology, Londdon, United Kingdom;(7)Western General Hospital, Department of Gastroenterology, Edinburgh, United Kingdom;(8)St George's University Hospitals NHS Foundation Trust, Department of Gastroenterology, London, United Kingdom;(9)Imperial College London, Department of Infectious Disease, London, United Kingdom;(10)Imperial College London, Department of Immunology and Inflammation, London, United Kingdom;CLARITY IBD
OP25: Prevalence of IBD in the Netherlands: development and validation of machine learning models for administrative dataECCO’23 Copenhagen
Year: 2023
Authors: Van Linschoten, R.(1,2,3)*;van Leeuwen, N.(2);Hazelzet, J.A.(2);van der Woude, C.J.(3);van Noord, D.(4);West, R.L.(4);
(1)Franciscus Gasthuis & Vlietland, Gastroenterology & Hepatology, Rotterdam, The Netherlands;(2)Erasmus MC, Department of Public Health, Rotterdam, The Netherlands;(3)Erasmus MC, Department of Gastroenterology & Hepatology, Rotterdam, The Netherlands;(4)Franciscus Gasthuis & Vlietland, Department of Gastroenterology & Hepatology, Rotterdam, The Netherlands;
OP26: Impact of telemonitoring with TECCU on the management of Inflammatory Bowel Disease in Spain: a GETECCU clinical trialECCO’23 Copenhagen
Year: 2023
Authors: Aguas Peris, M.(1,2)*;Del Hoyo, J.(1,2);Vicente, R.(3,4);Barreiro-de Acosta, M.(5);Melcarne, L.(6);Hernández-Camba, A.(7);Alfambra, E.(8,9);Madero, L.(10,11);Sicilia, B.(12);Chaparro, M.(13,14,15,16);Martín-Arranz, M.D.(14,17,18);Pajares, R.(19);Mesonero, F.(20);Mañosa, M.(16,21);Martínez, P.(22);Chacón , S.(23);Tosca, J.(24);Marín, S.(25,26);Sanromán, L.(27,28,29,30);Calvo, M.(31);Monfort, D.(32);Saiz, E.(33);Zabana, Y.(16,34);Guerra, I.(35);Varela, P.(36);Faubel, R.(37,38,39);Corsino, P.(3,4);Porto-Silva, S.(5);Brunet, E.(6);Gutiérrez, A.(10,11,16);Nos, P.(1,2);
(1)La Fe University and Polytechnic Hospital, Gastroenterology, Valencia, Spain;(2)Health Research Institute La Fe, IISLaFe, Valencia, Spain;(3)Miguel Servet University Hospital, Gastroenterology, Zaragoza, Spain;(4)Health Research Institute of Aragon, IIS Aragón, Zaragoza, Spain;(5)Santiago Clinic University Hospital, Gastroenterology, Santiago, Spain;(6)Parc Taulí Health Corporation, Gastroenterology, Sabadell, Spain;(7)Nuestra Señora de la Candelaria University Hospital, Gastroenterology, Tenerife, Spain;(8)Lozano Blesa Clinic University Hospital, Gastroenterology, Zaragoza, Spain;(9)IIS Aragón, Health Research Institute of Aragon IIS Aragon, Zaragoza, Spain;(10)Dr. Balmis General University Hospital, Gastroenterology, Alicante, Spain;(11)ISABIAL, Institute of Sanitary and Biomedical Research of Alicante, Alicante, Spain;(12)Burgos University Hospital, Gastroenterology, Burgos, Spain;(13)La Princesa University Hospital, Gastroenterology, Madrid, Spain;(14)Universidad Autónoma de Madrid, Faculty of Medicine, Madrid, Spain;(15)Princess Health Research Institute IIS-IP, IIS-La Princesa, Madrid, Spain;(16)Network Biomedical Research Center-ISCIII, CIBERehd, Madrid, Spain;(17)La Paz University Hospital, Gastroenterology, Madrid, Spain;(18)Investigación Sanitaria del Hospital Universitario La Paz, IdiPAZ, Madrid, Spain;(19)Infanta Sofía University Hospital, Gastroenterology, Madrid, Spain;(20)Ramón y Cajal University Hospital, Gastroenterology, Madrid, Spain;(21)Germans Trias i Pujol University Hospital-, Gastroenterology, Madrid, Spain;(22)San Cecilio Clinic University Hospital and Parque Tecnológico de la Salud, Gastroenterology, Granada, Spain;(23)Morales Meseguer General University Hospital, Gastroenterology, Murcia, Spain;(24)Clinic University Hospital, Gastroenterology, Valencia, Spain;(25)Reina Sofía University Hospital, Gastroenterology, Córdoba, Spain;(26)IMIBIC, Maimonides Institute for Biomedical Research of Córdoba, Córdoba, Spain;(27)Xerencia Xestion Integrada de Vigo-, Gastroenterology, Vigo, Spain;(28)IISGS, Galicia Sur Health Research Institute, Vigo, Spain;(29)Research Group in Digestive Diseases-, Digestive Diseases-, Vigo, Spain;(30)SERGAS, Galician Health Service, Vigo, Spain;(31)Puerta de Hierro University Hospital, Gastroenterology, Madrid, Spain;(32)Consorci Sanitari Terrasa-, Consorci Sanitari Terrasa-, Barcelona, Spain;(33)Xarxa Assistencial University Hospital, Gastroenterology, Manresa, Spain;(34)Mútua Terrassa University Hospital-, Gastroenterology, Barcelona, Spain;(35)Fuenlabrada University Hospital-, Gastroenterology, Fuenlabrada, Spain;(36)Cabueñes Universitary Hospital, Gastroenterology, Gijón, Spain;(37)ICT Applied to Reengineering Socio-Sanitary Process, Joint Research Unit, Valencia, Spain;(38)PTinMOTION-Physiotherapy in Motion Multispeciality Research Group- Universitat de València, Department of Physiotherapy, Valencia, Spain;(39)IIS La Fe-Universitat Politècnica de València, IISlaFe, Valencia, Spain;
OP27: Benefits of paediatric to adult transition program in Inflammatory Bowel Disease: The BUTTERFLY study of GETECCUECCO’23 Copenhagen
Year: 2023
Authors: Rubín De Célix, C.(1)*;Martín de Carpi, J.(2);Pujol, G.(2);Palomino, L.(3);Velasco, M.(3);Martín-Masot, R.(4);Navas-López, V.M.(4);Ricart, E.(5);Casanova, M.J.(1);Rodríguez Martínez, A.(6);Leo, E.(7);Alcaraz, A.(8);Mañosa, M.(9);Hernández, V.(10);Fernández, R.(10);Sánchez, C.(11);Menchén, L.(12);Mesonero, F.(13);Barreiro-De Acosta, M.(14);Martinon, N.(15);Tejido Sandoval, C.(16);Rendo Vázquez, A.(17);Corsino, P.(18);Vicente, R.(18);Hernández-Camba, A.(19);Alberto Alonso, J.R.(20);Alonso-Abreu, I.(21);Castro Millán, A.M.(22);Peries Reverter, L.(23);Castro, B.(24);Fernández-Salgado, E.(25);Busto Cuiñas, M.M.(26);Benítez, J.M.(27);Madero, L.(28);Clemente, F.(29);Riestra, S.(30);Jiménez-Treviño, S.(31);Boscá, M.(32);Chaparro, M.(1);Gisbert, J.P.(1);
(1)Hospital Universitario de La Princesa, Gastroenterology Department. Instituto de Investigación Sanitaria Princesa IIS-Princesa- Universidad Autónoma de Madrid UAM- and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas CIBEREHD, Madrid, Spain;(2)Hospital Sant Joan de Déu, Paediatric Gastroenterology- Hepatology and Nutrition Unit, Barcelona, Spain;(3)Hospital Infantil Universitario Niño Jesús, Paediatric Gastroenterology and Nutrition Unit, Madrid, Spain;(4)Hospital Regional Universitario de Málaga, Paediatric Gastroenterology and Nutrition Unit, Málaga, Spain;(5)Hospital Clinic, Gastroenterology Department, Barcelona, Spain;(6)Hospital Universitario Virgen del Rocío, Paediatric Gastroenterology- Hepatology and Nutrition- UGC de Pediatría, Sevilla, Spain;(7)Hospital Virgen del Rocío, Gastroenterology Department, Sevilla, Spain;(8)University Hospital Germans Trias I Pujol, Department of Paediatric Gastroenterology- Nutrition and Hepatology, Badalona, Spain;(9)Hospital Universitari Germans Trias I Pujol and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas CIBEREHD, Gastroenterology Department, Badalona, Spain;(10)Xerencia Xestion Integrada de Vigo. SERGAS. Research Group in Digestive Diseases- Galicia Sur Health Research Institute IIS Galicia Sur. SERGAS-UVIGO, Department of Gastroenterology, Vigo, Spain;(11)Hospital General Universitario Gregorio Marañón, Paediatric Gastroenterology- Hepatology and Nutrition, Madrid, Spain;(12)Hospital General Universitario Gregorio Marañón, Gastroenterology Department – CEIMI. Departamento de Medicina- Universidad Complutense de Madrid, Madrid, Spain;(13)Hospital Universitario Ramón y Cajal, Gastroenterology Department, Madrid, Spain;(14)Hospital Universitario Clínico de Santiago, Gastroenterology Department, Santiago de Compostela, Spain;(15)Hospital Universitario Clínico de Santiago, Paediatric Gastroenterology- Hepatology and Nutrition Unit, Santiago de Compostela, Spain;(16)Complejo Hospitalario Universitario de Ourense, Gastroenterology Department, Orense, Spain;(17)Complejo Hospitalario Universitario de Ourense, Paediatric Gastroenterology- Hepatology and Nutrition Unit, Orense, Spain;(18)Hospital Universitario Miguel Servet, Inflammatory Bowel Disease Unit. Gastroenterology Department, Zaragoza, Spain;(19)Hospital Universitario Nuestra Señora de Candelaria, Gastroenterology Department, Santa Cruz de Tenerife, Spain;(20)Hospital Universitario Nuestra Señora de Candelaria, Paediatric Gastroenterology- Hepatology and Nutrition Unit, Santa Cruz de Tenerife, Spain;(21)Hospital Universitario de Canarias, Gastroenterology Department, Santa Cruz de Tenerife, Spain;(22)Hospital Universitario de Canarias, Paediatric Gastroenterology- Hepatology and Nutrition Unit, Santa Cruz de Tenerife, Spain;(23)Hospital Universitari de Girona Doctor Josep Trueta, Gastroenterology Department, Girona, Spain;(24)Hospital Universitario Marqués de Valdecilla, Gastroenterology Department, Santander, Spain;(25)Complejo Hospitalario Universitario de Pontevedra, Gastroenterology Department, Pontevedra, Spain;(26)Complejo Hospitalario Universitario de Pontevedra, Paediatric Gastroenterology- Hepatology and Nutrition Unit, Pontevedra, Spain;(27)Hospital Universitario Reina Sofía. IMIBIC, Gastroenterology Department, Córdoba, Spain;(28)Hospital Universitario de Alicante, Gastroenterology Department, Alicante, Spain;(29)Hospital Universitario de Alicante, Paediatric Gastroenterology- Hepatology and Nutrition Unit, Alicante, Spain;(30)Hospital Universitario Central de Asturias and Instituto de Investigación Sanitaria del Principado de Asturias ISPA, Gastroenterology Department, Oviedo, Spain;(31)Hospital Universitario Central de Asturias, Paediatric Gastroenterology and Nutrition Unit, Oviedo, Spain;(32)Hospital Clínico de Valencia, Gastroenterology Department, Valencia, Spain;On Behalf Of the BUTTERFLY Study Group of GETECCU
OP28: Children and young adults with inflammatory bowel disease have an increased incidence and risk of developing mental health conditions: a UK population-based cohort studyECCO’23 Copenhagen
Year: 2023
Authors: Cooney, R.(1)*;Tang, D.(2);Barrett, K.(3);Russell, R.K.(4);
(1)Queen Elizabeth Hospital- Birmingham- UK, Department of Gastroenterology, Birmingham, United Kingdom;(2)Pfizer Ltd, Walton Oaks- Dorking Road, Tadworth, United Kingdom;(3)New Road Surgery, 166 New Road- Croxley Green, Rickmansworth, United Kingdom;(4)Royal Hospital for Children and Young People, Department of Paediatric Gastroenterology, Edinburgh, United Kingdom;
OP29: Peri-natal exposure to parental Crohn's disease is associated with impaired gut barrier, microbiome composition differences and increased risk of Crohn's diseaseECCO’23 Copenhagen
Year: 2023
Authors: LeeDr., S.H.(1)*;Qiu, L.(1);A. Olivera, P.(1);Leibovitzh, H.(1);Xue, M.(1);Neustaeter, A.(1);Mbareche, H.(1);Xu, W.(2);Espin-Garcia, O.(2); L. Aumais, G.(3);Q. Huynh, H.(4);Panaccione, R.(5);Steinhart, A.H.(1);Cino, M.(6);Mack, D.(7);K. Marshall, J.(8);Ropeleski, M.(9);Bitton, A.(10);Jacobson, K.(11);McGraft, J.(12);Yerushalmi, B.(13);Abreu, M.(14);N. Bernstein, C.(15);Radford-Smith, G.(16);Lees, C.(17);Turner, D.(18);L. Madsen, K.(4);S. Guttman, D.(19);S. Silverberg, M.(1);Turpin, W.(1);Croitoru, K.(1);
(1)Mount Sinai Hospital- University of Toronto, Division of Gastroenterology, Toronto, Canada;(2)Dalla Lana School of Public Health- University of Toronto, Division of Biostatistics, Toronto, Canada;(3)Hopital Maisonneuve-Rosemont, Department of Gastroenterology, Montreal, Canada;(4)University of Alberta, Department of Gastroenterology, Edmonton, Canada;(5)University of Calgary, Department of Gastroenterology, Calgary, Canada;(6)University of Toronto, Division of Gastroenterology & Hepatology, Toronto, Canada;(7)Children's Hospital of Eastern Ontario- University of Ottawa, Division of Gastroenterology- Hepatology & Nutrition, Ottawa, Canada;(8)McMaster University, Farncombe Family Digestive Health Research Institute, Hamilton, Canada;(9)Queen's University, Gastrointestinal Diseases Research Unit, Kingston, Canada;(10)McGill University and McGill University Health Centre, Division of Gastroenterology and Hepatology, Montreal, Canada;(11)British Columbia Children's Hospital- University of British Columbia, Department of Pediatrics, Vancouver, Canada;(12)General Hospital- Health Sciences Centre, Department of Gastroenterology, St. John's, Canada;(13)Soroka University Medical Center and Faculty of Health Sciences- Ben-Gurion University of the Negev, Pediatric Gastroenterology Unit, Beer-Sheva, Israel;(14)University of Miami, Division of Gastroenterology- Department of Medicine, Miami, United States;(15)University of Manitoba, Inflammatory Bowel Disease Clinical and Research Centre, Winnipeg, Canada;(16)QIMR Berghofer Medical Research Institute, Department of Gastroenterology, Brisbane, Australia;(17)University of Edinburgh, Department of Gastroenterology, Edinburgh, United Kingdom;(18)Shaare Zedek Medical Center- The Hebrew University of Jerusalem, The Juliet Keidan Institute of Pediatric Gastroenterology and Nutrition, Jerusalem, Israel;(19)University of Toronto, Centre for the Analysis of Genome Evolution and Function, Toronto, Canada;Crohn's Colitis Canada Genetic Environmental Microbial (CCC-GEM) Project Research Team
OP30: Human umbilical cord mesenchymal stem cells derived exosomes alleviate Ulcerative Colitis by inhibiting macrophage ferroptosis via miR-23b-3p/Nrf2 pathwayECCO’23 Copenhagen
Year: 2023
Authors: Liu, L.(1)*;Zhao, J.(1);Ye, Y.(1);Feng, Z.(1);Wang, X.(1);Cao, X.(1);
(1)Tianjin Medical University General Hospital, Department of Gastroenterology and Hepatology, Tianjin, China;
OP31: High fat diet exacerbates colitis through microbial metabolite deoxycholic acids induced-ferroptosisECCO’23 Copenhagen
Year: 2023
Authors: Wang, C.(1)*;Gu, Y.(1);Cao, H.(1);
(1)Tianjin Medical University General Hospital, Department of Gastroenterology and Hepatology, Tianjin, China;
OP32: The gut virome-colonizing Orthohepadnavirus genus is associated with ulcerative colitis pathogenesis and induces intestinal inflammation in vivoECCO’23 Copenhagen
Year: 2023
Authors: Facoetti, A.(1)*;Massimino, L.(2);Palmieri, O.(3);Fuggetta , D.(1);Spanò , S.(2);D'Alessio , S.(4);Furfaro, F.(5);D'Amico, F.(5);ZIlli, A.(5);Fiorino, G.(5);Noviello, D.(6);Latiano, A.(3);Bossa, F.(3);Pirola, A.(7);Mologni, L.(8);Piazza, R.(8);Abbati, D.(9);Perri, F.(3);Bonini , C.(9);Peyrin-Biroulet, L.(10);Malesci, A.(5);Danese, S.(5);Ungaro, F.(2);
(1)Università Vita-Salute San Raffaele, Department of Gastroenterology and Digestive Endoscopy in the Laboratory of Experimental Gastroenterology, Milan, Italy;(2)IRCCS Ospedale San Raffaele, Department of Gastroenterology and Digestive Endoscopy in the Laboratory of Experimental Gastroenterology, Milan, Italy;(3)Fondazione IRCCS Casa Sollievo della Sofferenza, Division of Gastroenterology, San Giovanni Rotondo FG, Italy;(4)Phoenix Lab, none, Lody, Italy;(5)IRCCS Ospedale San Raffaele, Department of Gastroenterology and Digestive Endcoscopy, Milan, Italy;(6)University of Milan, Department of Pathophysiology and Transplantation, Milan, Italy;(7)Galseq, None, Milan, Italy;(8)University of Milano - Bicocca, Department of Medicine and Surgery, Monza, Italy;(9)IRCCS Ospedale San Raffaele, Division of Immunology- Transplantation and Infectious Disease, Milan, Italy;(10)Inserm NGERE, University of Lorraine, Nancy, France;
OP33: Results of a randomised controlled trial to evaluate Interleukin 1 blockade with anakinra in patients with acute severe ulcerative colitis (IASO)ECCO’23 Copenhagen
Year: 2023
Authors: Raine, T.(1)*;Vaja, S.(2);Subramanian, S.(1);Brezina, B.(1);Probert, C.S.(3);Steel, A.(3);Lofthouse, M.(3);Speight, R.A.(4);Lamb, C.(4);Sebastian, S.(5);Kane, J.(5);Thut, J.(5);Din, S.(6);Arnott, I.(6);Smith, L.(6);Galea, J.(7);Hendy, P.(8);Flores, L.(9);Selinger, C.(10);Onoviran, F.(10);Steed, H.(11);Green, M.(12);Williams, J.(13);Jairath, V.(14);Qian, W.(2);Pavey, H.(2);Champion, K.(2);Dowling, F.(2);Thomas, M.(2);Wolf, K.(2);Davis-Wilkie, C.(2);Parkes, M.(1);Kaser, A.(15);
(1)Cambridge University Hospitals NHS Foundation Trust, Department of Gastroenterology, Cambridge, United Kingdom;(2)Cambridge University Hospitals NHS Foundation Trust, Cambridge Clinical Trials Unit, Cambridge, United Kingdom;(3)Royal Liverpool University Hospital, Department of Gastroenterology, Liverpool, United Kingdom;(4)Royal Victoria Infirmary, Department of Gastroenterology, Newcastle, United Kingdom;(5)Hull University Teaching Hospitals, IBD Unit, Hull, United Kingdom;(6)Western General Hospital- NHS Lothian, IBD Unit, Edinburgh, United Kingdom;(7)Cardiff and Vale University Health Board- Cardiff, Neurosurgery, Cardiff, United Kingdom;(8)Chelsea and Westminster NHS Trust, Department of Gastroenterology, London, United Kingdom;(9)Chelsea and Westminster NHS Trust, Research and Development, London, United Kingdom;(10)St James University Hospital, Department of Gastroenterology, Leeds, United Kingdom;(11)University of Wolverhampton, Department of Gastroenterology, Wolverhampton, United Kingdom;(12)The Royal Wolverhampton NHS Trust, Department of Gastroenterology, Wolverhampton, United Kingdom;(13)Swansea University, Department of Medicine, Swansea, United Kingdom;(14)Western University, Department of Gastroenterology, London, Canada;(15)University of Cambridge, Department of Medicine, Cambridge, United Kingdom;The IASO trial investigators
OP34: Enteral Nutrition Compared with Steroids in Children with Crohn's Disease – In Israel: a nationwide study from the epi-IIRNECCO’23 Copenhagen
Year: 2023
Authors: Plotkin, L.(1)*;Lujan, R.(1);Focht, G.(1);Greenfeld, S.(2);Loewenberg Weisband, Y.(3);Lederman, N.(4);Matz, E.(5);Dotan, I.(6);Turner, D.(1);
(1)Juliet Keidan Institute of Pediatric Gastroenterology Hepatology and Nutrition, Shaare Zedek Medical Center- The Hebrew University of Jerusalem- Israel, Jerusalem, Israel;(2)Maccabi Health Services and the Sackler Faculty of Medicine, Tel Aviv University, Tel-Aviv, Israel;(3)Clalit Health Services, Clalit Research Institute- Tel-Aviv- Israel, Tel-Aviv, Israel;(4)Meuhedet Health Services, Meuhedet Health Services, Tel-Aviv, Israel;(5)Leumit Health Services, Leumit Health Services, Tel-Aviv, Israel;(6)Division of Gastroenterology- Rabin Medical Center- Petah Tikva, and the Sackler Faculty of Medicine- Tel Aviv University, Tel-Aviv, Israel;
OP35: Efficacy and safety outcomes up to ~4 years of treatment with filgotinib 200 mg among patients with Ulcerative Colitis: Results from the SELECTIONLTE studyECCO’23 Copenhagen
Year: 2023
Authors: FeaganSenior Scientific Officer, B.G.(1)*;Matsuoka, K.(2);Rogler, G.(3);Faes, M.(4);Oortwijn, A.(5);de Haas, A.(6);Rudolph, C.(5);Peyrin-Biroulet, L.(7);
(1)Alimentiv Inc., Division of Gastroenterology, London, Canada;(2)Toho University Sakura Medical Center, Department of Gastroenterology and Hepatology, Chiba, Japan;(3)University Hospital Zurich, Department of Gastroenterology and Hepatology, Zurich, Sweden;(4)Galapagos NV, Biostatistics Department, Mechelen, Belgium;(5)Galapagos NV, Medical Affairs Department, Leiden, The Netherlands;(6)Galapagos NV, Clinical Development Department, Leiden, The Netherlands;(7)University Hospital of Nancy- University of Lorraine, Department of Gastroenterology, Vandoeuvre-lès-Nancy, France;
OP36: Real-world evidence on comparative effectiveness of Ustekinumab vs anti-TNF in Crohn's disease with propensity score adjustment: two-year maintenance phase results from the prospective observational RUN-CD studyECCO’23 Copenhagen
Year: 2023
Authors: Bokemeyer, B.(1,2,3)*;Plachta-Danielzik, S.(3);Deppe, H.(4);Mohl, W.(5);Teich, N.(6);Hoffstadt, M.(7);Schweitzer, A.(8);von der Ohe, M.(9);Gauss, A.(10);Atreya, R.(11);Krause, T.(12);Blumenstein, I.(13);Fajardo Salmon, S.(3);Hartmann, P.(4);Gilman, E.(3);Schreiber, S.(3,14);
(1)Prof. Dr. Bernd Bokemeyer, Interdisciplinary Crohn Colitis Centre Minden, Minden, Germany;(2)University Hospital Schleswig-Holstein- Campus Kiel, Clinic for General Internal Medicine I, Kiel, Germany;(3)Competence Network IBD, Study Department, Kiel, Germany;(4)Gastroenterology Practice Minden, Gastroenterology, Minden, Germany;(5)Centre for Gastroenterology Saar MVZ, Gastroenterology, Saarbrücken, Germany;(6)Gastroenterology Practice Leipzig, Gastroenterology, Leipzig, Germany;(7)Gastroenterology Practice Iserlohn, Gastroenterology, Iserlohn, Germany;(8)Gastroenterology Practice Münster, Gastroenterology, Münster, Germany;(9)Gastroenterology Practice Herne, Gastroenterology, Herne, Germany;(10)University Hospital Heidelberg, Department Internal Medicine IV - Gastroenterology Clinic, Heidelberg, Germany;(11)Friedrich-Alexander-University Erlangen-Nürnberg, Medical Clinic 1, Erlangen, Germany;(12)Gastroenterology Practice Kassel, Gastroenterology, Kassel, Germany;(13)Johann Wolfgang Goethe University Clinic Frankfurt, Department of Gastroenterology and Clinical Nutrition, Frankfurt, Germany;(14)University Hospital Schleswig-Holstein Campus Kiel, Clinic of General Internal Medicine I, Kiel, Germany;
OP37: Is the withdrawal of anti-tumour necrosis factor in inflammatory bowel disease patients in remission feasible without increasing the risk of relapse? Results from the randomised clinical trial of GETECCU (EXIT)ECCO’23 Copenhagen
Year: 2023
Authors: Chaparro, M.(1)*;García Donday, M.(1);Riestra, S.(2);Lucendo, A.J.(3);Benítez, J.M.(4);Navarro-Llavat, M.(5);Barrio, J.(6);Morales-Alvarado, V.J.(7);Rivero, M.(8);Busquets, D.(9);Leo Carnerero, E.(10);Merino Ochoa, O.(11);Nantes Castillejo, O.(12);Navarro, P.(13);Van Domselaar, M.(14);Gutiérrez Casbas, A.(15);Alonso-Abreu, I.(16);Mejuto, R.(17);Fernández Salazar, L.(18);Iborra, M.(19); Martín-Arranz, M.D.(20); Pineda, J.R.(21); Sampedro, M.J.(22);Serra Nilsson, K.(23);Bouhmidi Assakali, A.(24);Batista, L.(25);Muñoz Villafranca, C.(26);Rodríguez-Lago, I.(27); Ceballos Santos, D.S.(28);Guerra, I.(29);Mañosa, M.(30);Marín Jimenez, I.(31); Vera Mendoza, I.(32);Barreiro-de Acosta, M.(17);Domènech, E.(30);Esteve, M.(25);García-Sánchez, V.(4);Nos, P.(19);Panés, J.(33);Gisbert, J.P.(1);
(1)Hospital Universitario de La Princesa- IIS-Princesa- Universidad Autónoma de Madrid UAM- and CIBEREHD, Gastroenterology Unit, Madrid, Spain;(2)Hospital Universitario Central de Asturias and Instituto de Investigación Sanitaria del Principado de Asturias ISPA, Gastroenterology Unit, Oviedo, Spain;(3)Hospital General de Tomelloso- CIBERehd and Instituto de Investigación Sanitaria de Castilla-La Mancha IDISCAM, Gastroenterology Unit, Tomelloso, Spain;(4)Hospital universitario Reina Sofía and IMIBIC, Gastroenterology Unit, Córdoba, Spain;(5)Hospital de Sant Joan Despí Moisès Broggi, Gastroenterology Unit, Barcelona, Spain;(6)Hospital Universitario Río Hortega- Gerencia Regional de Salud de Castilla y León SACYL, Gastroenterology Unit, Valladolid, Spain;(7)Hospital General de Granollers, Gastroenterology Unit, Granollers, Spain;(8)Hospital Universitario Marqués de Valdecilla and IDIVAL, Gastroenterology Unit, Santander, Spain;(9)Hospital Universitari Dr. Josep Trueta, Gastroenterology Unit, Girona, Spain;(10)Hospital Universitario Virgen del Rocío, Gastroenterology Unit, Sevilla, Spain;(11)Hospital Universitario de Cruces, Gastroenterology Unit, Baracaldo, Spain;(12)Hospital Universitario de Navarra, Gastroenterology Unit, Pamplona, Spain;(13)Hospital Clínico Universitario de Valencia, Gastroenterology Unit, Valencia, Spain;(14)Hospital Universitario de Torrejón and Universidad Francisco de Vitoria, Gastroenterology Unit, Madrid, Spain;(15)Hospital General Universitario Dr Balmis- ISABIAL and CIBERehd, Gastroenterology Unit, Alicante, Spain;(16)Hospital Universitario de Canarias, Gastroenterology Unit, Santa Cruz de Tenerife, Spain;(17)Complexo Hospitalario Universitario de Santiago de Compostela, Gastroenterology Unit, Santiago de Compostela, Spain;(18)Hospital Clínico Universitario de Valladolid and Universidad de Valladolid, Gastroenterology Unit, Valladolid, Spain;(19)Hospital Universitari y Politecnic La Fe, Gastroenterology Unit, Valencia, Spain;(20)Hospital Universitario La Paz- Facultad de Medicina- Universidad Autónoma de Madrid and Instituto de Investigación Hospital universitario La Paz IdiPAZ, Gastroenterology Unit, Madrid, Spain;(21)Xerencia Xestión Integrada de Vigo- SERGAS- Research Group In Digestive Diseases- Galicia Sur Health Research Institute- SERGAS-UVIGO, Gastroenterology Unit, Vigo, Spain;(22)Hospital de Mataró, Gastroenterology Unit, Barcelona, Spain;(23)Hospital Universitari de Bellvitge, Gastroenterology Unit, L'Hospitalet de Llobregat, Spain;(24)Hospital de Santa Bárbara, Gastroenterology Unit, Puertollano, Spain;(25)Hospital Universitari Mutua Terrassa and CIBEREHD, Gastroenterology Unit, Barcelona, Spain;(26)Hospital Universitario de Basurto, Gastroenterology Unit, Bilbao, Spain;(27)Hospital Universitario de Galdakao and Instituto de Investigación Sanitaria Biocruces de Bizkaia, Gastroenterology Unit, Galdakao, Spain;(28)Hospital Universitario de Gran Canaria Dr. Negrín, Gastroenterology Unit, Las Palmas de Gran Canaria, Spain;(29)Hospital Universitario de Fuenlabrada and Instituto de Investigación Hospital Universitario La Paz IdiPAZ, Gastroenterology Unit, Madrid, Spain;(30)Hospital Universitari Germans Trias i Pujol and CIBEREHD, Gastroenterology Unit, Badalona, Spain;(31)Hospital Gregorio Marañón- Instituto de Investigación Sanitaria Gregorio Marañón IiSGM- Facultad de Medicina- Universidad Complutense, Gastroenterology Unit, Madrid, Spain;(32)Hospital Universitario Puerta de Hierro, Gastroenterology Unit, Majadahonda, Spain;(33)Hospital Clinic y Provincial, Gastroenterology Unit, Barcelona, Spain;on behalf of the EXIT Study group of GETECCU
OP38: Modulation of the septin cytoskeleton ameliorates intestinal fibrogenesisECCO’23 Copenhagen
Year: 2023
Authors: Naydenov, N.(1);Le, T.H.N.(1);Lechuga Villarauz, S.(1);Elias, M.(1);West, G.(1);Czarnecki, D.(1);Plesec, T.(1);Ivanov, A.(1);Rieder, F.(2)*;
(1)Cleveland Clinic, Inflammation and Immunity, Cleveland, United States;(2)Cleveland Clinic, Department of Gastroenterology- Hepatology and Nutrition, Cleveland, United States;
OP39: Safety of ustekinumab in IBD: Final pooled long-term safety analysis through 5 years in CD and 4 years in UCECCO’23 Copenhagen
Year: 2023
Authors: Ghosh, S.(1)*;Feagan, B.(2);Ott, E.(3);Gasink, C.(3);Marano, C.(4);Miao, Y.(4);Sandborn, W.(5);Danese, S.(6);Abreu, M.(7);Sands, B.(8);
(1)University College Cork, College of Medicine and Health, Cork, Ireland;(2)Western University and Alimentiv Inc., Gastroenterology, London, Canada;(3)Janssen, Scientific Affairs, Horsham, United States;(4)Janssen, Research & Development, Spring House, United States;(5)University of California San Diego, Division of Gastroenterology, La Jolla, United States;(6)IRCCS Ospedale San Raffaele and University Vita-Salute San Raffaele, Gastroenterology and Endoscopy, Milano, Italy;(7)University of Miami, Miller School of Medicine, Miami, United States;(8)Icahn School of Medicine at Mount Sinai, Dr. Henry D. Janowitz Division of Gastroenterology, New York, United States;
OP40: PRA023 Demonstrated Efficacy and Favorable Safety as Induction Therapy for Moderately to Severely Active UC: Phase 2 ARTEMIS-UC Study ResultsECCO’23 Copenhagen
Year: 2023
Authors: B. Sands*(1), L. Peyrin-Biroulet(2), S. Danese(3), D.T. Rubin(4), S. Vermeire(5), O. Laurent(6), A. Luo(6), D. Nguyen(6), JD. Lu(6),A. Wiechowska-Kozlowska(7), J. Leszczyszyn(8), R. Kempinski(9), J. Kierkus(10), C. Ma(11), T. Ritter*(12), B.G. Feagan(13), S. Targan*(14)
(1)Icahn School of Medicine at Mount Sinai, New York, New York, USA, (2)Last Inserm U954 and CHU de Nancy, Lorraine University, Nancy, France, (3)Gastroenterology and Gastrointestinal Endoscopy Unit, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milano, Italy, (4)University of Chicago Medicine Inflammatory Bowel Disease Center, Chicago, IL, USA, (5)University Hospitals Leuven, Department of Gastroenterology and Hepatology, Leuven, Belgium, (6)Prometheus Biosciences, Inc., San Diego, CA, USA, (7)Endoscopy Unit, SONOMED Medical Center, Szczecin, Poland, (8)Department of Gastroenterology, Melita Medical, Wroclaw, Poland, (9)Wroclaw Medical University, Department of Gastroenterology and Hepatology, Wroclaw, Poland, (10)Department of Gastroenterology, Hepatology, Feeding Disorders and Pediatrics, The Children's Memorial Health Institute, Warsaw, Poland, (11)Alimentiv Inc., London, ON, Canada Division of Gastroenterology & Hepatology, Department of Medicine and Community Health Sciences, University of Calgary, Calgary, AB, Canada, (12)GI Alliance, Southlake, Texas, USA, (13)Department of Medicine, Division of Gastroenterology, Western University, London, ON, Canada, (14)Division of Gastroenterology and Hepatology, Center for Inflammatory Bowel Diseases, Cedars-Sinai Medical Center, Los Angeles, CA,USA
P001: Obefazimod upregulates miR-124 and downregulates the expression of some cytokines in blood and rectal biopsies of patients with moderate-to-severe ulcerative colitis.ECCO’23 Copenhagen
Year: 2023
Authors: Santo, J.(1)*;Gineste, P.(1);Scherrer, D.(2);Nitcheu, J.(1);Ehrlich, H.(3);Sands, B.E.(4);Vermeire, S.(5);
(1)Abivax, Clinical Operations, Paris, France;(2)Abivax, Research and Development, Paris, France;(3)Abivax, Chief Executive Officer, Paris, France;(4)Icahn School of Medicine at Mount Sinai, Division of Gastroenterology, New York, United States;(5)UZ Leuven, Department of Gastroenterology & Hepatology, Leuven, Belgium;
P002: Exclusive Enteral Nutrition, the gut microbiome and corticosteroid response in patients with acute severe colitisECCO’23 Copenhagen
Year: 2023
Authors: Bajaj, A.(1)*;Markandey, M.(1);Vuyyuru, S.(1);Mohta, S.(1);Singh, M.(1);Verma, M.(1);Kumar, S.(1);Kante, B.(1);Kumar, P.(1);Makharia, G.(1);Kedia, S.(1);Travis, S.(2);Ahuja, V.(1);
(1)All India Institute of Medical Sciences, Department of Gastroenterology, New Delhi, India;(2)University of Oxford, The Kennedy Institute and Translational Gastroenterology Unit, Oxford OX2 7FY, United Kingdom;
P003: MicroRNAs as biomarkers in Inflammatory Bowel Disease unclassified (IBDU) patient samples may predict the development from IBDU to Crohn's Disease or Ulcerative ColitisECCO’23 Copenhagen
Year: 2023
Authors: Pallikkunnath James, J.(1)*;Riis, L.B.(1,2);Malham, M.(3,4);Høgdall, E.(1,2);Langholz, E.(2,5);Nielsen, B.S.(6);
(1)Herlev University Hospital, Department of Pathology, Herlev, Denmark;(2)University of Copenhagen, Institute for Clinical Medicine, Copenhagen, Denmark;(3)Copenhagen University Hospital - Amager and Hvidovre, The Pediatric Department, Hvidovre, Denmark;(4)University of Copenhagen, Copenhagen Center for Inflammatory Bowel Disease in Children- Adolescents and Adults- Hvidovre Hospital, Hvidovre, Denmark;(5)Herlev University Hospital, Department of Gasteroenterology, Herlev, Denmark;(6)Bioneer A/S, Molecular Histology, Hørsholm, Denmark;